Chemokine-chemokine receptors in cancer immunotherapy

Immunotherapy
Trina J Stewart, Mark J Smyth

Abstract

A surge in interest in the chemokine-chemokine receptor network is probably related to the expanding roles that chemokines have now been identified to play in human biology, particularly immunity. Specific tissue microenvironments express distinct chemokines and both hematopoietic and nonhematopoietic cells have receptor expression profiles that permit the coordinated trafficking and organization of cells within these specific tissues. Since the chemokine network plays critical roles in both the function of the immune system and the progression of cancer, it is an attractive target for therapeutic manipulation. This review will focus on chemokine and chemokine receptor network-related therapeutic interventions that utilize host-tumor interactions particularly involving the immune system.

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Citations

Jan 21, 2011·Cancer Metastasis Reviews·Trina J Stewart, Mark J Smyth
Jul 4, 2012·Journal of Molecular Histology·Qingchao ZhuYu Wang
Oct 15, 2011·Cancer Gene Therapy·T Nguyen-HoaiJ Westermann
Mar 5, 2013·The Journal of Clinical Investigation·Deborah A KnightMark J Smyth
Sep 6, 2012·Immunotherapy·Elham Mohit, Sima Rafati
May 11, 2012·Future Medicinal Chemistry·Victoria Vinader, Kamyar Afarinkia
May 11, 2012·Future Medicinal Chemistry·Victoria Vinader, Kamyar Afarinkia
Apr 9, 2016·Cancer Gene Therapy·T Nguyen-HoaiJ Westermann
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Apr 2, 2014·Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine·Houqun YingXueren Gao
Sep 28, 2013·Oncoimmunology·Ming LiTrina J Stewart
Jan 10, 2020·Archivum Immunologiae Et Therapiae Experimentalis·Atefeh ArabJavad Behravan
Dec 15, 2020·Pharmacology & Therapeutics·Gregory P TakacsJeffrey K Harrison

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Methods Mentioned

BETA
transgenic

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