Chemokines in neoplastic progression

Seminars in Cancer Biology
Albert Zlotnik

Abstract

Chemokines and their receptors have emerged as attractive targets regulating the migration of tumor cells in vivo, a process known as cancer metastasis. The control of metastasis is critical to the control of cancer progression. Two chemokine receptors and their ligands stand out as likely targets for therapeutics: CCR7/CCL21 for lymph node metastases, and CXCR4/CXCL12 for lung, liver, bone marrow, and brain metastases. The most widely expressed chemokine receptor among cancers is likely to be CXCR4.

References

Jun 3, 2000·Annual Review of Immunology·D Rossi, A Zlotnik
Nov 8, 2001·Journal of the National Cancer Institute·H E WileyS T Hwang
Apr 18, 2002·Leukemia·C VoermansC E van Der Schoot
Mar 11, 2003·American Journal of Respiratory and Critical Care Medicine·Roderick J PhillipsRobert M Strieter
Apr 4, 2003·International Journal of Cancer. Journal International Du Cancer·Iwao Takanami

❮ Previous
Next ❯

Citations

Dec 18, 2013·Breast Cancer Research and Treatment·Subir BiswasArindam Bhattacharyya
Sep 15, 2012·Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine·Helenisa Helena Oliveira-NetoAline Carvalho Batista
Nov 30, 2010·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·E VoulgarisN Pavlidis
Jan 5, 2005·The Journal of Clinical Investigation·Connie J Eaves
Jan 5, 2007·Genome Biology·Albert ZlotnikHisayuki Nomiyama
Aug 25, 2007·Cancer Metastasis Reviews·Simi Ali, Gwendal Lazennec
Oct 4, 2008·Journal of the American Society of Nephrology : JASN·Dipak DattaSoumitro Pal
Mar 13, 2009·Nature Reviews. Cancer·Johanna A Joyce, Jeffrey W Pollard
Feb 18, 2010·PloS One·Ulrike NaumannMarcus Thelen
Jul 4, 2012·Journal of Molecular Histology·Qingchao ZhuYu Wang
Jan 5, 2008·International Journal of Gastrointestinal Cancer·Daniel D BilladeauRaul Urrutia
Jan 7, 2011·Cancer Microenvironment : Official Journal of the International Cancer Microenvironment Society·Ashley S FelixFaina Linkov
Sep 25, 2007·Clinical & Experimental Metastasis·Adit Ben-Baruch
Sep 13, 2005·Cancer Immunology, Immunotherapy : CII·Ana CoelhoRui Medeiros
Oct 4, 2006·Cancer Metastasis Reviews·A Ben-Baruch
Oct 24, 2008·Histochemistry and Cell Biology·Hélène Maby-El Hajjami, Tatiana V Petrova
Feb 7, 2009·Omics : a Journal of Integrative Biology·Gau-Tyan LinHsueh-Wei Chang
Feb 25, 2009·Annals of Oncology : Official Journal of the European Society for Medical Oncology·N CabiogluM Cristofanilli
Jun 11, 2009·Journal of Huazhong University of Science and Technology. Medical Sciences = Hua Zhong Ke Ji Da Xue Xue Bao. Yi Xue Ying De Wen Ban = Huazhong Keji Daxue Xuebao. Yixue Yingdewen Ban·Xiaoyan ShenZehua Wang
Nov 19, 2008·Cell and Tissue Research·Leonid L Nikitenko
Mar 27, 2012·Expert Opinion on Therapeutic Targets·Alice ZoccoliDaniele Santini
Aug 9, 2005·Expert Opinion on Therapeutic Targets·Susanne J RogersSuzanne A Eccles
Nov 18, 2010·Expert Review of Anticancer Therapy·Yvonne Kienast, Frank Winkler
Jun 7, 2008·Expert Review of Anticancer Therapy·Karen L ReckampRobert A Figlin
May 23, 2015·Journal of Neuroimmune Pharmacology : the Official Journal of the Society on NeuroImmune Pharmacology·Ghazal BanisadrRichard J Miller
Apr 23, 2013·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·S K GantsevS R Kzyrgalin
Jan 22, 2013·Critical Reviews in Oncology/hematology·Fotis PerlikosKonstantinos N Syrigos
Aug 29, 2012·The Journal of Thoracic and Cardiovascular Surgery·Duha FahhamOri Wald
Dec 4, 2014·Molecular Neurobiology·Bahrami Tayyeb, Mehdipour Parvin

❮ Previous
Next ❯

Related Concepts

Related Feeds

Breast Invasive Carcinoma

Invasive breast cancers indicate a spread into breast tissues and lymph nodes. Here are the latest discoveries pertaining to breast invasive carcinomas.

Breast Invasive Carcinoma (Keystone)

Invasive breast cancers indicate a spread into breast tissues and lymph nodes. Here are the latest discoveries pertaining to breast invasive carcinomas.