Chemometric profile, antioxidant and tyrosinase inhibitory activity of Camel's foot creeper leaves (Bauhinia vahlii)

Natural Product Research
Pritipadma PandaGoutam Ghosh

Abstract

The present study is the first effort to a comprehensive evaluation of antityrosinase activity and chemometric analysis of Bauhinia vahlii. The experimental results revealed that the methanol extract of Bauhinia vahlii (BVM) possesses higher polyphenolic compounds and total antioxidant activity than those reported elsewhere for other more conventionally and geographically different varieties. The BVM contain saturated fatty acids such as hexadecanoic acid (10.15%), octadecanoic acid (1.97%), oleic acid (0.61%) and cis-vaccenic acid (2.43%) along with vitamin E (12.71%), α-amyrin (9.84%), methyl salicylate (2.39%) and β-sitosterol (17.35%), which were mainly responsible for antioxidant as well as tyrosinase inhibitory activity. Tyrosinase inhibitory activity of this extract was comparable to that of Kojic acid. These findings suggested that the B. vahlii leaves could be exploited as potential source of natural antioxidant and tyrosinase inhibitory agent, as well.

References

Aug 10, 2007·Phytochemical Analysis : PCA·Patricia Kaori Soares, Ieda Spacino Scarminio
Oct 30, 2009·International Journal of Molecular Sciences·Jody P EbanksRaymond E Boissy
Oct 12, 2010·Pharmacognosy Magazine·Swarnalatha DugasaniMallikarjuna Rao Pichika
Aug 13, 2011·Pigment Cell & Melanoma Research·Andrzej SlominskiJohn Pawelek
Jan 9, 2016·Natural Product Research·Raja RadhaKasi Pitchumani

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Citations

Feb 9, 2019·Journal of Enzyme Inhibition and Medicinal Chemistry·Samaneh ZolghadriAli Akbar Saboury
Jun 22, 2021·Journal of Biomolecular Structure & Dynamics·Suchismeeta BeheraPrafulla K Mohanty

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