Chemoprevention in Barrett's oesophagus

Best Practice & Research. Clinical Gastroenterology
Anushka Baruah, Navtej S Buttar

Abstract

Increasing incidence of oesophageal adenocarcinoma along with poor survival entails novel preventive strategies. Agents that target pro-oncogenic pathways in Barrett's mucosa could halt this neoplastic transformation. In this review, we will use epidemiological associations and molecular mechanisms to identify novel chemoprevention targets in Barrett's oesophagus. We will also discuss recent chemoprevention trials.

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Citations

Sep 14, 2016·Annual Review of Medicine·Nabil M MansourSharmila Anandasabapathy

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