PMID: 2484394Apr 1, 1989Paper

Chemoprevention trial of human hepatitis with selenium supplementation in China

Biological Trace Element Research
S Y YuC Hou

Abstract

A three-year study has been conducted for prevention of infectious hepatitis with supplementation of table salt fortified with 15 ppm anhydrous sodium selenite to the general population of 20,847 persons in a township M.Z. at Qidong County, Jiangsu Province, China. The results showed that the incidence of virus hepatitis infection in the test township was significantly lower than that of controls provided with normal table salt. The incidence rate of infectious hepatitis in the treated township M.Z. was 1.20 and 4.52 per 1,000, whereas the average incidence in the 6 surrounding control townships was 2.96 and 10.48 per 1,000 in 1986 and 1987, respectively. The incidence of hepatitis B surface antigen (HBsAg+) was 13.2% vs 19.23% for males and 10.42% vs 12.24% for females in the supplemented vs nonsupplemented neighboring township, respectively. Epidemiological studies have demonstrated that a low grain Se content is associated with a high regional incidence of hepatitis B virus infections.

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Citations

Jan 1, 1997·Biological Trace Element Research·E W TaylorC S Ramanathan
Sep 8, 2011·Biological Trace Element Research·Naseem RaufShoukat Parvez
Feb 16, 2013·Biological Trace Element Research·Danzhen Pan, Hanju Huang
Jan 30, 2004·The British Journal of Nutrition·P D Whanger
Nov 5, 2010·Journal of Translational Medicine·Giuseppe CastelloStefania Scala
Mar 17, 2012·Saudi Journal of Gastroenterology : Official Journal of the Saudi Gastroenterology Association·Mohammad S KhanNaseem Rauf
Nov 26, 2015·Nutrition and Cancer·Junxuan LüMaarten C Bosland
Mar 1, 2012·Journal of Trace Elements in Medicine and Biology : Organ of the Society for Minerals and Trace Elements (GMS)·Beáta Éva PetrovskiZoltán Vokó
Feb 11, 2005·International Journal of Cancer. Journal International Du Cancer·Lori C SakodaKatherine A McGlynn
Jun 1, 2010·Molecular Nutrition & Food Research·Howard P GlauertBrett T Spear
Jan 18, 2003·Journal of Trace Elements in Medicine and Biology : Organ of the Society for Minerals and Trace Elements (GMS)·Ahmet KalkanNamik Kemal Bingol

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