Chemopreventive and Anti-tumor Potential of Natural Products in Oral Cancer.

Nutrition and Cancer
Andrés Cardona-MendozaSandra J Perdomo

Abstract

Oral cancer (OC) is a multifactorial disease caused by isolated or combined risk factors related to tobacco, alcohol consumption, and human papillomavirus infection. It is an aggressive pathology with a low five-year survival rate after surgery, chemotherapy, and/or radiotherapy, frequently associated with severe side effects. Drugs with the highest anti-tumor effect are obtained from natural products with diverse biological and molecular activities and potential chemopreventive and anticancer properties. This review summarizes the natural products reported to have the chemopreventive and anti-tumor potential for OC treatment, showing that several of these compounds are promising candidates as chemopreventive agents, and those with the highest anti-tumor potential induce apoptosis and inhibit proliferation and metastasis-related processes. For this reason, natural products have the potential to be important preventive and therapeutic options for OC in the future.

References

Jul 6, 2000·Nature·M V EberhardtR H Liu
Nov 7, 2001·Australian Dental Journal·N Andrews, C Griffiths
Mar 1, 2003·Journal of Natural Products·Chihiro ItoHiroshi Furukawa
Jan 7, 2005·The American Journal of Chinese Medicine·Jung-San ChangChun-Ching Lin
Mar 16, 2005·Cancer Letters·Mia HashibeZuo-Feng Zhang
Oct 6, 2005·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Maria M LoTempioMarilene B Wang
Nov 10, 2005·International Journal of Oral and Maxillofacial Surgery·Y HuaC Zhi
Mar 23, 2006·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Wilhelm J LubbeGiovanni M Pitari
Feb 21, 2007·Journal of Natural Products·David J Newman, Gordon M Cragg
Jun 15, 2007·Toxicologic Pathology·Susan Elmore
Apr 17, 2008·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Brian S ShumwaySusan R Mallery
Apr 30, 2008·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·P ManikandanS Nagini
Jun 12, 2008·Journal of the National Cancer Institute·Vicki Brower
Oct 3, 2008·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Dorothy WangMarilene B Wang
Oct 14, 2008·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Deepak KademaniUNKNOWN American Association of Oral and Maxillofacial Surgeons Task Force on Oral Cancer
Jan 1, 2009·Nutrition and Cancer·Jayadev Raju, Rekha Mehta
May 6, 2009·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·A R M Ruhul AminDong M Shin
Nov 7, 2009·Cancer Prevention Research·Anne S TsaoVassiliki Papadimitrakopoulou
Jan 28, 2010·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Shun-Fa YangShu-Chen Chu
Mar 30, 2010·Plant Physiology and Biochemistry : PPB·Fiona R Saunders, Heather M Wallace
Jul 14, 2010·International Journal of Dental Hygiene·S L PriebeN T P Thao
Nov 20, 2010·The FEBS Journal·Chrisostomi GialeliNikos K Karamanos
Mar 8, 2011·Cell·Douglas Hanahan, Robert A Weinberg
Mar 11, 2011·Journal of Agricultural and Food Chemistry·Pei-Ni ChenYih-Shou Hsieh
Apr 15, 2011·Advances in Dental Research·N W JohnsonL Kowalski
Jul 8, 2011·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Rob Glynne-Jones
Jul 12, 2011·Medicina oral, patología oral y cirugía bucal·Enrique Jané-SalasEduardo Chimenos-Küstner
Nov 23, 2011·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·Yaoh-Shiang LinShin Nieh

❮ Previous
Next ❯

Related Concepts

Related Feeds

Apoptosis

Apoptosis is a specific process that leads to programmed cell death through the activation of an evolutionary conserved intracellular pathway leading to pathognomic cellular changes distinct from cellular necrosis

Related Papers

Expert Opinion on Investigational Drugs
Jacquelyn M Guilford, John M Pezzuto
American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists
Donna Young
La Revue du praticien
Robert Benamouzig, Stanislas Chaussade
© 2021 Meta ULC. All rights reserved