PMID: 9173710Mar 1, 1997Paper

Chemoreflex and baroreflex sensitivity in patients with survived sudden cardiac death

Zeitschrift für Kardiologie
M G HennersdorfB E Strauer

Abstract

To evaluate patients with an increased risk of sudden cardiac death the analysis of ventricular late potentials, heart rate variability and baroreflexsensitivity is helpful. However, the prediction of malignant arrhythmic events cannot be performed with sufficient accuracy. For a better identification of high risk patients other methods are necessary. In this study the impact of the chemoreflexsensitivity for the prediction of ventricular tachyarrhythmias was investigated. Out of 44 patients included in the study, 23 were survivors of sudden cardiac death (SCD). Seven patients suffered from sustained monomorphic ventricular tachycardias, 14 had no arrhythmic events in their prior history. For the investigation of the baroreflexsensitivity (BRS) systolic blood pressure was augmented by Norfenefrin (Novadral) and the resulting increase of RR-intervals was measured in the surface-ECG. For determination of the chemoreflexsensitivity (ChRS) the ratio of the RR-interval-shift and the blood pressure shift during a 5-min inhalation of oxygen with a nose mask was formed. Patients with aborted SCD showed significantly decreased values for the ChRS compared to those patients without an arrhythmic event in their prior history (2.49 +/- 1.8...Continue Reading

Citations

May 4, 2000·Pacing and Clinical Electrophysiology : PACE·M G HennersdorfB E Strauer
May 6, 2010·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Axel BuobM Böhm
Apr 25, 2000·American Journal of Hypertension·J TankM Weck
Dec 12, 2001·European Journal of Heart Failure·M G HennersdorfB E Strauer

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