PMID: 7537146Jan 1, 1995Paper

Chemorepellents in Paramecium and Tetrahymena

The Journal of Eukaryotic Microbiology
J T Francis, Todd M Hennessey

Abstract

Although Paramecium has been widely used as a model sensory cell to study the cellular responses to thermal, mechanical and chemoattractant stimuli, little is known about their responses to chemorepellents. We have used a convenient capillary tube repellent bioassay to describe 4 different compounds that are chemorepellents for Paramecium and compared their response with those of Tetrahymena. The classical Paramecium t-maze chemokinesis test was also used to verify that this is a reliable chemorepellent assay. The first two compounds, GTP and the oxidant NBT, are known to be depolarizing chemorepellents in Paramecium but this is the first report of them as repellents in Tetrahymena. The second two compounds, the secretagogue alcian blue and the dye cibacron blue, have not previously been described as chemorepellents in either of these ciliates. Two other compounds, the secretagogue AED and the oxidant cytochrome c, were found to be repellents to Paramecium but not to Tetrahymena. The repellent nature of each of these compounds is not related to toxicity because cells are completely viable in all of them. More importantly, all of these repellents are effective at micromolar to nanomolar concentrations, providing an opportunity t...Continue Reading

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Citations

Jul 20, 2000·Archives of Biochemistry and Biophysics·T Bernas, J W Dobrucki
Apr 12, 2008·Purinergic Signalling·Todd M Hennessey
Mar 10, 1999·Chemosphere·M P SauvantE Piccinni
Dec 19, 2000·Biochemical and Biophysical Research Communications·M IwamotoY Nakaoka
Feb 7, 2008·The Journal of Eukaryotic Microbiology·Lindsay F RodgersTodd M Hennessey
Aug 14, 2015·PloS One·Peter HinowJ Rudi Strickler
Mar 14, 2019·Scientific Reports·Mst Shaela Pervin, Shigehiko Yumura
Dec 28, 2002·The Journal of Experimental Biology·Christopher R Wood, Todd M Hennessey
Nov 6, 2002·European Journal of Cell Biology·Masaaki Iwamoto, Yasuo Nakaoka

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