Chemoselective hydrogenation of carbonyl compounds and acceptorless dehydrogenative coupling of alcohols

Journal of the American Chemical Society
Denis SpasyukDmitry G Gusev

Abstract

OsHCl(CO)[κ(3)-PyCH2NHC2H4NHPtBu2] is the first efficient catalyst for chemoselective reduction of challenging unsaturated esters to enols and for acceptorless coupling of amines with MeOH and EtOH affording formamides and acetamides. The NMR, ESI-MS, and DFT data indicate a mechanism proceeding in the metal coordination sphere and producing no free organic intermediates.

References

Aug 4, 2005·Journal of the American Chemical Society·Jing ZhangDavid Milstein
Jan 4, 2006·Angewandte Chemie·Jing ZhangDavid Milstein
Aug 11, 2007·Science·Chidambaram GunanathanDavid Milstein
Oct 27, 2007·Accounts of Chemical Research·Lionel A Saudan
Feb 10, 2012·Angewandte Chemie·Denis SpasyukDmitry G Gusev
Jan 29, 2013·Angewandte Chemie·Denis SpasyukDmitry G Gusev
Mar 26, 2013·Organic Letters·Nuria OrtegaFrank Glorius
Jan 22, 2014·Journal of Mass Spectrometry : JMS·Lars P E YunkerJ Scott McIndoe

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Citations

Apr 21, 2017·Angewandte Chemie·Magnus B WidegrenMatthew L Clarke
Nov 1, 2016·Chemistry : a European Journal·Noel Angel Espinosa-JalapaDavid Milstein
Apr 7, 2017·Chemistry : a European Journal·Pim PuylaertJohannes G de Vries
Sep 5, 2015·Dalton Transactions : an International Journal of Inorganic Chemistry·W Xu, R Langer
Jul 17, 2018·Dalton Transactions : an International Journal of Inorganic Chemistry·Xiuli Yan, Xinzheng Yang
Aug 30, 2019·Chemical Communications : Chem Comm·Shubham DeolkaEugene Khaskin
Sep 17, 2020·Organic & Biomolecular Chemistry·Guo-Ping YangYu-Feng Liu
Jan 10, 2017·Angewandte Chemie·Stacey A Morris, Dmitry G Gusev
Jun 17, 2020·Chemical Communications : Chem Comm·Guanghui WangEric Meggers
Oct 19, 2016·Chemical Record : an Official Publication of the Chemical Society of Japan ... [et Al.]·Xiangyang Chen, Xinzheng Yang
Jan 8, 2021·The Journal of Organic Chemistry·Zhengqiang FuNing Liu
Jul 2, 2021·Dalton Transactions : an International Journal of Inorganic Chemistry·Duc Hanh NguyenRégis M Gauvin
Jun 9, 2015·Journal of the American Chemical Society·Georgy A FilonenkoEvgeny A Pidko
Oct 8, 2019·Journal of the American Chemical Society·Tianyi HeAnthony R Chianese
Oct 8, 2019·Organic Letters·Yoon Kyung JangMagnus Rueping
Nov 10, 2020·Journal of the American Chemical Society·Louise N DaweDmitry G Gusev
Sep 4, 2021·Dalton Transactions : an International Journal of Inorganic Chemistry·Elizabeth C TroddenStephen M Mansell

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