Chemosensory induced arousals during sleep in premenopausal women

Neuroscience Letters
Kathrin GruppB A Stuck

Abstract

Only a limited number of studies is available addressing chemosensory stimulation during sleep. Recent work indicates that stimulation with a nasal irritant produces an increase in arousal frequency in non-REM sleep, whereas a selective olfactory stimulant does not. The present study focused on arousal reactions in REM sleep. Five young healthy volunteers were investigated during 27 nights. Using air-dilution olfactometry CO(2) was used for nasal irritation and H(2)S was used as a specific olfactory stimulant. Both stimuli were presented at four concentrations, odorless stimuli served as control. Other than in previous studies arousal latency was used as a dependent measure. Even the strongest olfactory stimulus did not produce an increase in arousal frequency in REM sleep whereas for irritation such an increase was clearly present. Latencies of arousal responses to CO(2) shortened with increasing stimulus concentrations. Olfactory stimulation does not lead to arousal reactions. In contrast, trigeminal stimulation produces a concentration-dependent increase in arousal frequency and decrease in arousal latency across all sleep stages. The present data shows for the first time that arousals are not present during REM sleep in res...Continue Reading

References

Jul 1, 1990·Physiology & Behavior·P BadiaJ Harsh
May 5, 1998·Electroencephalography and Clinical Neurophysiology·T HummelG Kobal
Aug 7, 1999·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·J W CovingtonC Murphy
Jan 1, 2000·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·M FerraraM Bertini
Jun 27, 2000·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·G KobalT Hummel
Feb 24, 2001·Canadian Journal of Experimental Psychology = Revue Canadienne De Psychologie Expérimentale·C H BastienK B Campbell
Jul 19, 2001·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·C DanielsR Ferstl
Oct 18, 2001·Acta Oto-laryngologica·M WolfensbergerA Welge-Lüssen
Sep 2, 2004·Journal of Sleep Research·T KatoG J Lavigne
May 3, 2006·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·B A StuckT Hummel
Aug 29, 2006·Neuroscience Letters·Boris A StuckThomas Hummel
May 25, 2007·Sleep·Boris A StuckThomas Hummel

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Citations

Nov 18, 2009·Chemical Senses·Anat ArziNoam Sobel
Apr 30, 2020·Laryngo- rhino- otologie·Hilmar GudziolThomas Bitter

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