Chemotherapy against babesiosis

Veterinary Parasitology
Henri J Vial, A Gorenflot

Abstract

Babesiosis is caused by a haemotropic protozoal parasite of the genus Babesia, member of the phylum Apicomplexa and transmitted by the bite of an infected tick. There are many Babesia species affecting livestock, dogs, horses and rodents which are of economic significance. Infections can occur without producing symptoms, but babesiosis may also be severe and sometimes fatal caused by the intraerythrocytic parasite development. The disease can cause fever, fatigue and haemolytic anemia lasting from several days to several months. There are a number of effective babesiacides, but imidocarb dipropionate (which consistently clears the parasitaemia; often the only available drug on the market) and diminazene aceturate are the most widely used. Some Babesia spp. can infect humans, particularly Babesia microti and Babesia divergens, and human babesiosis is a significant emerging tick-borne zoonotic disease. Clinical manifestations differ markedly between European and North American diseases. In clinical cases, a combination of clindamycin and quinine is administered as the standard treatment, but also administration of atovaquone-azithromycin is successful. Supportive therapy such as intravenous fluids and blood transfusions are emplo...Continue Reading

References

Jun 20, 1977·Journal of Medical Entomology·O H Graham, J L Hourrigan
Jun 28, 1976·Cell and Tissue Research·M A RudzinskaE Gubert
Jan 1, 1989·The Veterinary Quarterly·G UilenbergA A Spanjer
Dec 1, 1987·Annals of Internal Medicine·D RaoultP Casanova
Oct 1, 1982·Annals of Internal Medicine·K S RowinM Wittner
Mar 1, 1981·Annals of Internal Medicine·P B FrancioliD J Wolf
May 1, 1982·Annals of Internal Medicine·M WittnerG R Healy
Oct 1, 1995·The Journal of Infectious Diseases·W T Hughes, H S Oz
Nov 1, 1993·The Journal of Infectious Diseases·L M WeissH B Tanowitz
Mar 1, 1997·Transactions of the Royal Society of Tropical Medicine and Hygiene·M F Shaio, K D Yang
Nov 22, 1997·Parasitology·T P SchettersA Gorenflot
Apr 30, 1998·Journal of the South African Veterinary Association·R J MilnerJ S van den Berg
May 20, 1998·Journal of Clinical Apheresis·D A EvensonD F Stroncek
Apr 2, 1999·Journal of the American Animal Hospital Association·A J BirkenheuerE B Breitschwerdt
Aug 25, 1999·Current Opinion in Microbiology·D S RoosB Striepen
Nov 18, 2000·The New England Journal of Medicine·P J KrauseA Spielman
Dec 13, 2000·International Journal for Parasitology·A M Kjemtrup, P A Conrad
Mar 10, 2001·The New England Journal of Medicine·L M WeissH B Tanowitz
Apr 3, 2001·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·J C HatcherV E Jimenez-Lucho
Apr 18, 2002·Antimicrobial Agents and Chemotherapy·Aaron L Baggish, David R Hill
Jul 5, 2002·Clinical Microbiology Reviews·Frederick L Schuster
Aug 2, 2002·Expert Opinion on Pharmacotherapy·Louis M Weiss
Feb 15, 2003·Trends in Parasitology·David R Allred
May 10, 2003·Cellular and Molecular Life Sciences : CMLS·I Pankova-KholmyanskyE Flescher
May 29, 2003·Current Drug Targets. Immune, Endocrine and Metabolic Disorders·Frank Seeber
Jul 25, 2003·Antimicrobial Agents and Chemotherapy·Marie L AncelinHenri J Vial
Oct 15, 2003·Clinical Microbiology Reviews·Annetta ZintlJeremy S Gray
Aug 19, 2004·The Biochemical Journal·Avadhesha SuroliaNamita Surolia
Oct 20, 2004·Proceedings of the National Academy of Sciences of the United States of America·Henri J VialMichèle Calas
Feb 22, 2005·Combinatorial Chemistry & High Throughput Screening·Xavier J Salom-RoigHenri J Vial

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Citations

Nov 6, 2013·The Journal of Veterinary Medical Science·Ketsarin KamyingkirdXuenan Xuan
Apr 18, 2014·The Journal of Veterinary Medical Science·Jing WangJi-yu Zhang
Jul 30, 2014·Parasitology·Monica Florin-ChristensenLeonhard Schnittger
Feb 17, 2015·The Onderstepoort Journal of Veterinary Research·Louise J BiggsVinny Naidoo
May 9, 2007·Infection and Immunity·Naotoshi TsujiKozo Fujisaki
Jul 22, 2009·Antimicrobial Agents and Chemotherapy·O Nicolas SchwintGlen A Scoles
Oct 12, 2010·Clinical Microbiology Reviews·J L N BarrattD Stark
May 4, 2011·Antimicrobial Agents and Chemotherapy·Angela Nehrbass-StuedliReto Brun
Nov 5, 2013·Experimental Parasitology·Monica L MazuzVarda Shkap
Oct 10, 2013·Infection·A HildebrandtK-P Hunfeld
Jun 8, 2012·The Journal of Veterinary Medical Science·Bandula Kumara Wickramasekara RajapakshageMitsuyoshi Takiguchi
Jun 26, 2008·Tropical Animal Health and Production·Hamad Bin RashidAsim Khalid Mahmood
Nov 1, 2013·Parasitology Research·Akram Ahmed SalamaIkuo Igarashi
Aug 13, 2011·Drug and Chemical Toxicology·Ozlem Derinbay Ekici, Nermin Isik
May 17, 2011·Veterinary Parasitology·Laia Solano-Gallego, Gad Baneth
Sep 22, 2010·European Journal of Pharmacology·Xuanmao ChenJohn F MacDonald
Jun 15, 2010·Parasitology International·Youn-Kyoung GooXuenan Xuan
Feb 25, 2010·Parasitology International·Mahmoud AbouLailaIkuo Igarashi
Nov 10, 2009·Veterinary Parasitology·Mahmoud AboulailaIkuo Igarashi
Dec 25, 2008·Experimental Parasitology·Claudia SánchezAbel G Oliva
Oct 17, 2015·Pharmacological Research : the Official Journal of the Italian Pharmacological Society·George Laylson da Silva Oliveira, Rivelilson Mendes de Freitas
Jul 5, 2008·Research in Veterinary Science·Mostafa A Saleh
Mar 17, 2015·Tierärztliche Praxis. Ausgabe K, Kleintiere/Heimtiere·Ł AdaszekS Winiarczyk
Mar 13, 2016·Journal of Molecular Modeling·Potshangbam Angamba MeeteiVaibhav Vindal
Nov 19, 2013·Journal of Veterinary Emergency and Critical Care·Thomas DasteMarcel Aumann
Sep 12, 2006·Veterinary Parasitology·Filipe Dantas-Torres, Luciana Aguiar Figueredo
Sep 18, 2015·Infectious Diseases of Poverty·Nyamongo W OnkobaSamson Mukaratirwa
Jun 8, 2012·Veterinary Parasitology·Thillaiampalam SivakumarNaoaki Yokoyama
Jul 16, 2013·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Thillaiampalam SivakumarNaoaki Yokoyama
Jun 19, 2014·Veterinary Parasitology·Mahmoud AbouLailaIkuo Igarashi
Oct 12, 2011·Acta Tropica·Tiago M MartinsAna Domingos
Nov 7, 2007·The Journal of Veterinary Medical Science·Noriyuki TakabatakeIkuo Igarashi

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