Chemotherapy-induced acral erythema in a pediatric patient with acute monoblastic leukemia

Pediatric Hematology and Oncology
Fatih DemircioğluGülersu Irken

Abstract

Chemotherapy-induced acral erythema or palmoplantar erythrodysesthesia syndrome is a well-defined reaction to some of the chemotherapeutic agents such as methotrexate, cytarabine, doxorubicin, fluorouracil, and bleomycin. This reaction is characterized by symmetrical, well-demarcated, painful erythema of the palms and soles, which may progress to desquamation. The authors present a case of acral erythema in a young patient with acute monoblastic leukemia to emphasize this high-dose chemotherapy-induced side effect, which is rarely seen in children and is usually self-limited.

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Citations

Jun 3, 2009·Pediatric Blood & Cancer·Rajat SahaGauri Kapoor

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