Chemotherapy-induced nausea in a sample of gynaecological cancer patients: assessment issues and personal risk factors evaluation

Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer
Valentina E Di MatteiMassimo Candiani

Abstract

Chemotherapy-induced nausea (CIN) is a relevant problem for gynaecological cancer patients. The evaluation of CIN is a key aspect in its management, along with the identification of associated risk factors. The objective of the study was to compare different measurements of nausea and to investigate personal risk factors in CIN development. Eighty-one women treated for gynaecological cancers took part. The presence of CIN was evaluated using the MASCC Antiemesis Tool (MAT) and a patient's report to clinicians at the subsequent chemotherapy cycle. Personal risk factors were assessed using the State-Trait Anxiety Inventory and a self-report questionnaire. The study shows that the agreement between patients' assessment of CIN with MAT and what they referred to clinicians was only moderate for acute nausea (Cohen's Kappa = 0.55; p < 0.001), while good for delayed nausea (Cohen's Kappa = 0.68; p < 0.001). At multiple logistic regression analysis, younger age, anticipatory nausea, patient medium-high expectations of CIN, and parity emerged as risk factors for the development of acute nausea (p = 0.0087, 0.0080, 0.0122 and 0.0021, respectively). Patient medium-high expectations of CIN and being single resulted to be risk factors for d...Continue Reading

References

Feb 1, 1989·Nihon eiseigaku zasshi. Japanese journal of hygiene·M IwamotoT Morie
Jun 1, 1970·Journal of Consulting and Clinical Psychology·G J Allen
Jan 1, 1994·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·R K PortenoyL Norton
Jul 7, 1993·Journal of the National Cancer Institute·C Vanchieri
Aug 30, 2000·Annals of Behavioral Medicine : a Publication of the Society of Behavioral Medicine·J A RoscoeG R Morrow
Jul 12, 2003·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·C Pitceathly, P Maguire
Nov 13, 2004·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Charlotte C SunEdward B Rubenstein
Nov 30, 2005·Annals of Oncology : Official Journal of the European Society for Medical Oncology·F RoilaUNKNOWN Antiemetic Subcommitte of the Multinational Association of Supportive Care in Cancer
Sep 20, 2006·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Brigitte Bloechl-DaumJørn Herrstedt
Jan 15, 2009·Psycho-oncology·Brenda L Den OudstenJolanda De Vries
Aug 25, 2009·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Joseph A RoscoeAndrew Jacobs
Sep 17, 2009·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Paul J HeskethAlexandra D Carides
May 13, 2010·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·David G WarrAlexandra D Carides
Jun 29, 2010·Annals of Oncology : Official Journal of the European Society for Medical Oncology·F RoilaUNKNOWN ESMO/MASCC Guidelines Working Group
Nov 19, 2010·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Margarita MajemAgustí Barnadas
Aug 30, 2011·Annals of Behavioral Medicine : a Publication of the Society of Behavioral Medicine·Wai Kai Hou, Jacky Ho Yin Wan
May 23, 2012·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Carole FarrellAlex Molassiotis
May 30, 2013·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·A MolassiotisE Kontopantelis
Oct 1, 2013·Expert Opinion on Drug Safety·Stefania RussoFabio Puglisi
Oct 26, 2013·European Journal of Pharmacology·David Warr
Mar 11, 2015·Annals of Oncology : Official Journal of the European Society for Medical Oncology·K JordanM Aapro
Sep 19, 2015·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·George DranitsarisMark Clemons
Dec 25, 2015·Critical Reviews in Oncology/hematology·Silvia SommarivaRosanna Tarricone
May 25, 2016·Journal of Multidisciplinary Healthcare·Alaa Althubaiti
Sep 25, 2016·Annals of Oncology : Official Journal of the European Society for Medical Oncology·F RoilaUNKNOWN participants of the MASCC/ESMO Consensus Conference Copenhagen 2015
Jan 22, 2017·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Snežana M BošnjakLee Schwartzberg
May 27, 2017·Clinical Trials : Journal of the Society for Clinical Trials·Tito R MendozaEthan Basch
Jul 25, 2017·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Qiang WenShihua Wang
Oct 5, 2018·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Yasmeen RazviKatarzyna Joanna Jerzak
Apr 14, 2019·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Hannah WoopenJ Sehouli
Jun 1, 2015·Annals of Oncology : Official Journal of the European Society for Medical Oncology·K JordanM Aapro

❮ Previous
Next ❯

Citations

Mar 5, 2021·Current Opinion in Oncology·Ian Olver

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.