Chemotherapy related fatal neurotoxicity during induction in acute lymphoblastic leukemia

Indian Journal of Pediatrics
Munni RayAmita Trehan

Abstract

Neurotoxicity is a common complication during cancer chemotherapy. It is estimated that 3-10% of children with acute lymphoblastic leukemia (ALL) experience acute, transient neurotoxicity during induction chemotherapy. Fatal acute neurotoxicity is rarely encountered. Neurological evaluation of children with ALL at diagnosis and during treatment is of value in order to diagnose neurological complications early so that appropriate intervention can be adopted. This communication describes the profile of two children with unexpected, acute fatal neurologic toxicity during induction chemotherapy for ALL.

References

Nov 1, 1977·Archives of Disease in Childhood·R H CampbellJ M Chessells
Aug 1, 1991·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·G M McCarthy, J R Skillings
Feb 19, 1992·Journal of the National Cancer Institute·N J WinickG R Buchanan
Jan 1, 1990·Journal of Pediatric Oncology Nursing : Official Journal of the Association of Pediatric Oncology Nurses·S B Young
Nov 1, 1986·Medical Toxicology·S S Legha
Jan 1, 1982·Cancer Chemotherapy and Pharmacology·Z R DesaiR G Shanks
Jan 1, 1993·Acta Haematologica·T SoysalN Akman
Jun 1, 2000·Acta Paediatrica·A W Craft

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Citations

Feb 14, 2003·Current Neurology and Neuroscience Reports·Alyssa T Reddy, Kerry Witek
Nov 26, 2009·Indian Journal of Pediatrics·Sunil GomberDevender Chhonker
Sep 30, 2005·Ethnicity & Health·Tonje Mellin-Olsen, Margareta Wandel
Dec 20, 2002·Current Opinion in Oncology·Yaddanapudi Ravindranath
May 28, 2004·Pharmacotherapy·Stacia Brock, Heath R Jennings
Jul 24, 2015·Pediatric Neurology·Birol BaytanMehmet Okan
Oct 14, 2005·Journal of the Peripheral Nervous System : JPNS·David BalayssacFrançois Coudore

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