[Chiari II malformation. Supportive and predictive value of brainstem reflex and EAEP recordings].

Der Nervenarzt
J KoehlerA Faldum

Abstract

In about 20% of patients with Chiari II malformation brainstem signs and symptoms occur. Ventilatory dysfunction is the main cause of death in these patients. The indication for craniocervical decompression is based on clinical examination because supporting electrophysiological or radiological methods were lacking. In a prospective study the clinical courses of 106 patients were documented during a 3-year period. In addition brainstem diagnostic procedures using the masseter reflex (MR), blink reflex (BR) and early auditory evoked potentials (EAEP) were done. Based on the model of binary logistic regression the odds ratio (OR) of progression over time was calculated. The combination of MR and late BR components showed the highest correlation with clinical findings (OR: 23). The highest predictive value regarding clinical progression over a 3-year period was shown by the combined evaluation of MR, late BR components and EAEP interpeak latency I-V (OR: 17.6). Signs and symptoms had no predictive value. Combined brainstem reflex recordings (MR and late BR components) support the clinical examination. To evaluate the long-term prognosis brainstem reflexes and EAEP recordings should be used.

References

Jan 1, 1990·Pediatric Neurosurgery·D D CochraneP Steinbok
Jan 1, 1989·Pediatric Neuroscience·D G McLone, P A Knepper
Apr 1, 1989·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·R de la CruzM J Muñoz
Oct 1, 1987·Journal of Neurology, Neurosurgery, and Psychiatry·T B DochertyE M Sedgwick
Aug 1, 1986·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·D D EisenstatH Schutz
Nov 1, 1982·Journal of Neurosurgery·J F CusickS J Larson
May 1, 1994·Muscle & Nerve·H C Hopf
Jan 1, 1993·Developmental Medicine and Child Neurology·A B BarnetC Shaer
Jan 1, 1996·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·T Nishimura, K Mori
Feb 9, 2000·The Journal of Laryngology and Otology·G G BuyseC Plets
May 29, 2004·Pediatric Neurology·Jürgen Koehler, Cordula Hölker

❮ Previous
Next ❯

Related Concepts

Related Feeds

Auditory Perception

Auditory perception is the ability to receive and interpret information attained by the ears. Here is the latest research on factors and underlying mechanisms that influence auditory perception.

Related Papers

Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
N M SperlingT H Milhorat
Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery
Gregory G HeuerLeslie N Sutton
© 2021 Meta ULC. All rights reserved