Chick wing innervation. II. Morphology of motor and sensory axons and their growth cones during early development

The Journal of Comparative Neurology
M Hollyday, M Morgan-Carr

Abstract

The development and distribution of neuronal projections to the developing chick wing was studied using anterograde transport of horseradish peroxidase (HRP). Small injections of HRP were made into motor or sensory neuronal populations in order to visualize individual axons and their associated growth cones. Motor growth cones were observed in different regions of the embryo at different stages, in a proximal-to-distal pattern of distribution which paralleled the process of axon outgrowth and nerve formation. Different growth cone morphologies were associated with differing regions of the developing projection. In the spinal nerves, axons destined for the limb were unbranched and terminated in simply shaped growth cones. As axons approached the developing limb and entered the plexus region, their growth cones became more complex and larger primarily because of widening, and they sometimes branched, producing processes which could extend tens of microns from a tricorne branch point on the parent axon. Both motor and sensory fibers showed similar morphological changes in the plexus region. A distinctively shaped growth cone expanded on its leading edge was observed, sequentially apparent in the distal spinal nerves, in the plexus...Continue Reading

References

Aug 1, 1978·Experimental Cell Research·N K Wessells, R P Nuttall
Sep 1, 1977·The Journal of Physiology·J L Rosenthal, P S Taraskevich
Dec 15, 1990·The Journal of Comparative Neurology·M Hollyday
Mar 1, 1973·The Journal of Cell Biology·D Bray
Dec 10, 1982·Science·D Bentley, H Keshishian

Citations

Sep 16, 1996·The Journal of Comparative Neurology·J G Whitesides, A S LaMantia
Jan 17, 2002·The Journal of Comparative Neurology·Giovanna ZanioloLucia Manni
Jun 26, 1995·The Journal of Comparative Neurology·M J Ferns, M Hollyday
Aug 4, 2006·Glia·Ina B WannerKristjan R Jessen
Dec 2, 2009·Developmental Neurobiology·Phillip LamoureuxKyle E Miller
Jun 5, 2004·Neuroimaging Clinics of North America·Ruby J LienBradley N Delman
Feb 16, 2002·Developmental Biology·M G HonigQing-Shan Xue
Nov 16, 2007·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Isabel BrachmannKerry Lee Tucker

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