Childhood Absence Epilepsy evolving to Eyelid Myoclonia with Absence Epilepsy

Seizure : the Journal of the British Epilepsy Association
Jessica GalliLucio Giordano

Abstract

Children with Childhood Absence Epilepsy (CAE) may develop generalized tonic-clonic seizure or juvenile myoclonic epilepsy. A possible evolution to Eyelid Myoclonia with Absence Epilepsy (EMA) hasn't been documented yet. We report the electroclinical features of a case series of children with CAE that evolved to EMA after therapy withdrawal. Of 108 patients with CAE referred at our Epilepsy Center in the last ten years, 5 satisfied the inclusion criteria: CAE diagnosis, a minimum of 3 years follow-up, a progression to EMA after therapy withdrawal. All the six subjects were females. CAE was characterized by typical absences induced by hyperventilation; intermittent photic stimulation (IPS) was negative. All subjects were treated successfully with valproate. After drug withdrawal, all the six girls presented EMA. EMA was characterized by eyelid myoclonia with or without brief absences related to generalized spike/polyspike-waves discharges induced by IPS and less frequently by eye-closure. Our study documented another possible evolution of CAE into EMA. These results support the hypothesis that these two epileptic conditions are dynamic processes evolving into one another. CAE and EMA could be considered "system epilepsy" charact...Continue Reading

References

Feb 1, 1977·Developmental Medicine and Child Neurology·P M Jeavons
Dec 20, 2002·Neurophysiologie clinique = Clinical neurophysiology·Salvatore StrianoPatrizia Ruosi
Jun 24, 2006·Seizure : the Journal of the British Epilepsy Association·A Destina YalçinElif Kiliç
May 8, 2009·Seizure : the Journal of the British Epilepsy Association·Roberto H CaraballoBernardo Dalla Bernardina
Aug 24, 2010·Epilepsia·Friederike MoellerJean Gotman
May 7, 2011·Epilepsy Research·Lucio GiordanoPasquale Striano
Apr 27, 2012·Epilepsia·Giuliano AvanziniGiuseppe Capovilla
Aug 19, 2014·Annals of Neurology·Anna Elisabetta VaudanoStefano Meletti
Feb 28, 2017·European Journal of Paediatric Neurology : EJPN : Official Journal of the European Paediatric Neurology Society·Alberto VerrottiGiancarlo Di Gennaro

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Citations

Feb 8, 2020·Acta Neurologica Scandinavica·Ali A Asadi-Pooya, Maryam Homayoun
May 24, 2021·Seizure : the Journal of the British Epilepsy Association·Josefina de la JaraJuan Moya-Vilches

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