Childhood acute bacterial meningitis in the Sudan: an epidemiological, clinical and laboratory study

Scandinavian Journal of Infectious Diseases. Supplementum
M A Salih

Abstract

The aims of the present study were to document the epidemiology, clinical features and complications of childhood acute bacterial meningitis (ABM) in The Sudan during both an inter-epidemic (endemic) period (1985-1986), and the 1988 serogroup A epidemic; and to examine the phenotypic and genetic similarities and differences of Neisseria meningitidis strains isolated in The Sudan and Sweden. A new enzyme immunoassay test (Pharmacia Meningitis EIA-Test) was evaluated as a potential rapid diagnostic method for the detection of Haemophilus influenzae (HI) type b, Neisseria meningitidis (MC) and Streptococcus pneumoniae (PNC). The test was found to have good sensitivity (0.86) and specificity (0.95) in the inter-epidemic period; and to be adaptable to the field work in The Sudan during the 1988 MC epidemic. During inter-epidemic (endemic) situations in The Sudan, greater than 90% of childhood ABM was caused by one of the three organisms, HI type b, MC and PNC. HI accounted for 57% of the cases. The peak incidence (76%) of HI cases was in infants (less than 12 months) similar to the situation in other African countries. The overall case fatality ratio was 18.6%. Prospective follow-up of survivors for 3-4 years revealed that an additi...Continue Reading

References

Feb 1, 1979·American Journal of Diseases of Children·G A AhronheimM I Marks
Sep 1, 1979·Journal of Clinical Microbiology·S A HardingM A Sande
Jun 30, 1975·Annals of the New York Academy of Sciences·D Danielsson, U Forsum
Jan 1, 1978·Scandinavian Journal of Infectious Diseases·P OlcénS Anséhn
Jan 1, 1977·Scandinavian Journal of Infectious Diseases·M Leinonen, E Herva
May 20, 1978·British Medical Journal·B M GreenwoodH C Whittle
Aug 25, 1979·British Medical Journal·J R Oakley, A N Stanton
Jan 1, 1979·Transactions of the Royal Society of Tropical Medicine and Hygiene·B M GreenwoodQ Ansari
Jan 1, 1979·Transactions of the Royal Society of Tropical Medicine and Hygiene·M Hassan-KingE M Sutcliffe
Jan 1, 1977·Scandinavian Journal of Infectious Diseases·J P GhanassiaJ Modai
Jan 1, 1978·Scandinavian Journal of Infectious Diseases·D MontefioreE Sobayo
Nov 1, 1978·Acta paediatrica Scandinavica·H Hailemeskel, N Tafari
Apr 1, 1977·Archives of Disease in Childhood·L G Evans-JonesB M Greenwood
Jul 1, 1977·The American Journal of Tropical Medicine and Hygiene·D W BelcherH A FELDMAN
Aug 1, 1975·The Journal of Speech and Hearing Disorders·R J RoeserD D Daly
Apr 1, 1976·The Journal of Pediatrics·R D FeiginH Davis
Jan 18, 1990·The New England Journal of Medicine·U B SchaadJ Wedgwood
Jul 1, 1985·Reviews of Infectious Diseases·C E FraschJ T Poolman
May 1, 1986·Applied and Environmental Microbiology·R K SelanderT S Whittam
Mar 1, 1987·Annals of Tropical Paediatrics·C S RyderH D Heese
Apr 1, 1988·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·H AbdillahiJ T Poolman
Feb 1, 1989·The Journal of Infectious Diseases·P BrandtzaegE Sørensen
Oct 28, 1989·Lancet·N I GirgisM E Kilpatrick
Nov 25, 1989·Lancet·E J Stokes
Dec 1, 1989·The Pediatric Infectious Disease Journal·N I GirgisM E Kilpatrick
Dec 1, 1989·The Pediatric Infectious Disease Journal·M A SandeG H McCracken
Apr 1, 1989·The Journal of Pediatrics·G F HaydenR H Henderson
Jun 1, 1989·The Journal of Pediatrics·M H LebelG H McCracken
May 1, 1989·Reviews of Infectious Diseases·R Austrian
Oct 1, 1989·Pediatric Clinics of North America·R W Steele, G L Kearns
Nov 1, 1989·The Journal of Pediatrics·A K TakalaP H Mäkelä
Jun 8, 1985·Lancet·M GrattenT Lupiwa
Oct 12, 1985·Lancet·B M GreenwoodR A Wall
Mar 1, 1989·American Journal of Diseases of Children·S L Kaplan
Oct 13, 1988·The New England Journal of Medicine·M H LebelG H McCracken
Jan 1, 1988·Scandinavian Journal of Infectious Diseases·N I GirgisJ N Woody
Jul 1, 1988·British Medical Bulletin·D A MitchisonJ Grosset
Mar 15, 1986·British Medical Journal·K P KlugmanA C Mauff
Jul 1, 1986·Proceedings of the National Academy of Sciences of the United States of America·D A CaugantR K Selander
May 1, 1987·The Pediatric Infectious Disease Journal·D Van EssoM Duran
Apr 1, 1988·The Journal of Antimicrobial Chemotherapy·P N Gaunt, B E Lambert
Aug 1, 1988·Journal of Clinical Microbiology·E RosenqvistW D Zollinger
Jan 1, 1988·Transactions of the Royal Society of Tropical Medicine and Hygiene·A W SmithB M Greenwood
Aug 1, 1987·The Pediatric Infectious Disease Journal·S H Sell
Aug 1, 1987·The Pediatric Infectious Disease Journal·C V Broome
Aug 1, 1987·The Pediatric Infectious Disease Journal·G Peter
Aug 1, 1987·The Pediatric Infectious Disease Journal·J B Robbins, R Schneerson
Aug 1, 1987·The Pediatric Infectious Disease Journal·J C Parke
Oct 1, 1987·British Medical Bulletin·S C Bellman
Feb 1, 1988·The Pediatric Infectious Disease Journal·S A Harrison, W L Risser
Oct 13, 1988·The New England Journal of Medicine·A L Smith
Jan 1, 1987·Transactions of the Royal Society of Tropical Medicine and Hygiene·B M GreenwoodR A Wall
Jan 1, 1987·Reviews of Infectious Diseases·J M GriffissP H Mäkelä
Jan 1, 1987·Scandinavian Journal of Infectious Diseases·K M SalwénP Olcén
Mar 1, 1987·International Journal of Epidemiology·S L CochiV L Gurubacharya
Apr 1, 1987·Ear and Hearing·M N Obiako
Apr 1, 1986·Journal of Pediatric Surgery·B W Loggie, E J Hinchey
Sep 1, 1985·The Journal of Infection·V A Nottidge
Sep 1, 1985·The Journal of Pediatrics·D M Granoff, K L Cates
Jun 1, 1985·European Journal of Clinical Microbiology·U Berger
Sep 1, 1985·Diagnostic Microbiology and Infectious Disease·D J HobanG W Hammond
Nov 1, 1973·The New England Journal of Medicine·R NachumS E Siegel
Aug 18, 1973·British Medical Journal·H C WhittleA D Rajković
Feb 1, 1974·American Journal of Diseases of Children·W H Toews, J W Bass
Mar 16, 1974·British Medical Journal·D M EastonJ B Kurtz
Jun 1, 1974·The Journal of Infectious Diseases·R S MunfordR A Feldman
Jul 6, 1972·The New England Journal of Medicine·L S YoungJ V Bennett
Dec 1, 1972·Journal of Clinical Pathology·W P Severin
Oct 1, 1972·Neurology·J F Schwartz
Mar 1, 1973·The Journal of Infectious Diseases·D W FraserR A Feldman
Jan 1, 1971·Transactions of the Royal Society of Tropical Medicine and Hygiene·Y Mpairwe, H L Matovu
Apr 1, 1971·The Journal of Infectious Diseases·T C Eickhoff
Jun 1, 1984·Journal of Clinical Microbiology·B BjorvatnB Lindqvist
Nov 1, 1984·The Journal of Infectious Diseases·B E KristiansenE Holten
Jun 16, 1984·Lancet·B M GreenwoodH C Whittle
Dec 1, 1981·Annals of Tropical Paediatrics·F E Berkowitz
Jan 1, 1983·Reviews of Infectious Diseases·H Peltola
Apr 1, 1983·Annals of Tropical Medicine and Parasitology·I S BlakebroughH M Gilles
May 1, 1983·Journal of Clinical Microbiology·F E AshtonH J Jennings
Dec 1, 1983·Infection and Immunity·R J SugasawaraJ E Sippel
Jan 1, 1984·Transactions of the Royal Society of Tropical Medicine and Hygiene·J B PuddicombeB M Greenwood
Oct 4, 1984·The New England Journal of Medicine·P R DODGES K Hirsh
Jul 1, 1984·Pediatric Infectious Disease·T Y LinG H McCracken
Dec 1, 1984·Journal of Tropical Pediatrics·M I MullaA Moosa
Jun 14, 1984·The New England Journal of Medicine·H PeltolaP H Mäkelä
Jan 1, 1983·Scandinavian Journal of Infectious Diseases·J H BraconierC Söderström
Mar 1, 1984·Pediatric Infectious Disease·M A JacksonG H McCracken
Apr 1, 1981·Journal of Bacteriology·C M TsaiL F Mocca
Jan 1, 1982·Reviews of Infectious Diseases·J M Griffiss
Nov 11, 1982·The New England Journal of Medicine·R D FeiginS E Whitney
Jun 1, 1980·The Journal of Infection·I S Blakebrough, H M Gilles
Jun 1, 1982·Developmental Medicine and Child Neurology·A TejaniJ Sambursky
Nov 1, 1980·Reviews of Infectious Diseases·U B Schaad
Mar 1, 1981·Reviews of Infectious Diseases·D W Wara
Oct 1, 1981·The Journal of Pediatrics·M S Edwards, C J Baker
Jan 1, 1971·Scandinavian Journal of Infectious Diseases·P M NiklassonT Strandell
May 1, 1956·Canadian Journal of Microbiology·S E BRANHAM
Jun 1, 1963·Journal of Bacteriology·D S KELLOGGD I PIRKLE
Oct 12, 1963·JAMA : the Journal of the American Medical Association·J W MILLARP FRANK
Apr 1, 1932·The Journal of Hygiene·D Riding, N L Corkill
Sep 1, 1940·The Journal of Hygiene·R M Buchanan

Related Concepts

Acute Disease
Disease Outbreaks
Sensory Hearing Loss
Peroxidase-Antiperoxidase Complex Technique
Pachymeningitis
Meningitis, Haemophilus Parainfluenzae
Meningitis, Meningococcal, Serogroup Y
Meningitis, Pneumococcal, Penicillin-Resistant
Neisseria meningitidis

Related Feeds

Bacterial Meningitis

Bacterial meningitis continues to be an important cause of mortality and morbidity throughout the world. Here is the latest research.

Auditory Perception

Auditory perception is the ability to receive and interpret information attained by the ears. Here is the latest research on factors and underlying mechanisms that influence auditory perception.

Bacterial Meningitis (ASM)

Bacterial meningitis continues to be an important cause of mortality and morbidity throughout the world. Here is the latest research.