Childhood Immunization and COVID-19: An Early Narrative Review.

Frontiers in Public Health
Bojana Beric-StojsicSanjoy Roy

Abstract

The COVID-19 pandemic has evolved into arguably the largest global public health crisis in recent history-especially in the absence of a safe and effective vaccine or an effective anti-viral treatment. As reported, the virus seems to less commonly infect children and causing less severe symptoms among infected children. This narrative review provides an inclusive view of scientific hypotheses, logical derivation, and early analyses that substantiate or refute such conjectures. At the completion of a relatively less restrictive search of this evolving topic, 13 articles-all published in 2020, were included in this early narrative review. Directional themes arising from the identified literature imply the potential relationship between childhood vaccination and COVID-19-either based on the potential genomic and immunological protective effects of heterologous immunity, or based on observational associations of cross-immunity among vaccines and other prior endemic diseases. Our review suggests that immune response to the SARS-CoV-2 virus in children is different than in adults, resulting in differences in the levels of severity of symptoms and outcomes of the disease in different age groups. Further clinical investigations are war...Continue Reading

References

May 16, 2017·Archives of Disease in Childhood·Andrew J PollardNigel Curtis
Aug 18, 2018·Future Microbiology·Egle ButkeviciuteSteven G Smith
Mar 10, 2020·Journal of Microbiology, Immunology, and Infection = Wei Mian Yu Gan Ran Za Zhi·Ping-Ing LeePo-Ren Hsueh
Mar 19, 2020·Euro Surveillance : Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin·Kenji MizumotoGerardo Chowell
Mar 27, 2020·Acta Paediatrica·Petter Brodin
Mar 29, 2020·Nature·Smriti Mallapaty
Apr 3, 2020·Transplant International : Official Journal of the European Society for Organ Transplantation·Pedram Ahmadpoor, Lionel Rostaing
Apr 3, 2020·Medical Hypotheses·Samar Salman, Mohamed Labib Salem
Apr 14, 2020·Experimental and Clinical Transplantation : Official Journal of the Middle East Society for Organ Transplantation·Faik SarialiogluMehmet Haberal
May 10, 2020·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Tulika SinghSallie R Permar
May 12, 2020·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Nisha S MehtaJonathan S Nguyen-Van-Tam
May 13, 2020·Nature Reviews. Immunology·Luke A J O'Neill, Mihai G Netea
May 14, 2020·JAMA : the Journal of the American Medical Association·Uri HamielIlan Youngster
May 28, 2020·The Lancet Child & Adolescent Health·Rita CarsettiFranco Locatelli
May 29, 2020·Nature Reviews. Immunology·Peter AabyFrank Shann
Jun 9, 2020·MedRxiv : the Preprint Server for Health Sciences·Luis E EscobarCarolina Barillas-Mury
Jul 11, 2020·Proceedings of the National Academy of Sciences of the United States of America·Luis E EscobarCarolina Barillas-Mury
Mar 28, 2020·MedRxiv : the Preprint Server for Health Sciences·A. MillerGonzalo H Otazu

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Citations

Jul 9, 2021·Global Health, Science and Practice·Giridhara R BabuBhramar Mukherjee
Aug 23, 2021·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·Jeff SlezakSara Tartof

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