Childhood lead poisoning associated with traditional Chinese medicine: a case report and the subsequent lead source inquiry

Clinica Chimica Acta; International Journal of Clinical Chemistry
Guo-zhen LinXiang-yi Liu

Abstract

Traditional medicines or ethnic remedies, such as Ayurvedic drug of India, have been reported in numerous cases to be one of the main exposure risks for severe lead poisoning. We describe the poisoning of 2 young children from a Chinese family in Guangzhou as a result of the use of traditional Chinese medicine instead of baby powder. A 3-y-old boy with blood lead levels (BLLs) of 303 μg/l and his 6-month-old sister with BLLs of 385 μg/l were hospitalized. Laboratory tests showed that the powder, which was purchased in Ganzhou during a family visit, contained a lead concentration of 214,000 mg/kg. A subsequent inspection revealed that the lead contamination was in fact achieved by the addition of Hongdan to talcum. In Ganzhou, it was a popular practice for young children to apply this leaded powder on their skins in order to treat and prevent dermatitis. We sampled 16 Hongdans and observed an average lead content of 817,000 mg/kg that was comprised mainly of lead tetraoxide (Pb(3)O(4)). Lead tetraoxide is also an accessible raw material for paint and battery industries. The health authority of China should reevaluate the safety of such traditional remedy and weigh its toxicity versus its potential benefits. Clinicians should be ...Continue Reading

References

Feb 2, 1990·JAMA : the Journal of the American Medical Association·H L Needleman, C A Gatsonis
Dec 18, 1993·Lancet·T Y ChanJ A Critchley
Mar 7, 2002·Trends in Pharmacological Sciences·Edzard Ernst
Dec 13, 2002·Brain : a Journal of Neurology·Theodore I Lidsky, Jay S Schneider
Jan 18, 2003·AIHA Journal : a Journal for the Science of Occupational and Environmental Health and Safety·Chee-Ching SunJung-Der Wang
Sep 27, 2005·The Science of the Total Environment·Vikram NichaniLuke P Naeher
Jul 9, 2008·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·Alan D WoolfChulathida Chomchai
Jul 9, 2008·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·Emmanuel C Gorospe, Shawn L Gerstenberger
Sep 17, 2009·Lancet·Jonathan Watts
Apr 16, 2011·Lancet·Ailing JiTongjian Cai

❮ Previous
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Citations

Aug 16, 2015·Environmental Health : a Global Access Science Source·Renée A StreetCatherine Connolly
Oct 6, 2016·Environmental Geochemistry and Health·Mateusz P KarwowskiAlan D Woolf
Nov 25, 2016·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·Eduardo Mello De Capitani
Sep 27, 2018·Acta Paediatrica·Rachael FarringtonRoger W Byard
Oct 29, 2017·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·Xiao-Lan YingChong-Huai Yan
Jan 6, 2017·Environmental Science and Pollution Research International·Tao LiYaohua Dai
Oct 31, 2017·The Tohoku Journal of Experimental Medicine·Guangmin TangPing Feng
Jan 31, 2021·Journal of Hazardous Materials·Chih-Min YangChao-Hsiang Chen

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