Childhood obesity patterns and relation to middle-age sleep apnoea risk: the Bogalusa Heart Study

Pediatric Obesity
L A BazzanoS Redline

Abstract

Obese adults have a higher risk of obstructive sleep apnoea (OSA); however, the relationship between childhood obesity and adult OSA risk is unclear. Objectives This study aimed to examine overweight/obesity (OW) in childhood and risk of OSA in middle age. Childhood OW status was classified as never OW, weight cycling, persistent OW and incident OW. After 35 years of follow-up, high risk for OSA was determined by a positive score in ≥2 domains on the Berlin Questionnaire with obesity removed from scoring. At initial assessment, mean (SD) age was 9.9 (2.9) years, and 23.9% were OW. Overall, 25.7% had scores indicating a high risk for OSA. Compared with participants who were never OW, those with persistent OW and incident OW were 1.36 (95%CI: 1.04-1.77) and 1.47 (1.11-1.96) times more likely to be high risk for OSA, after adjustment for multiple risk factors and adult OW status. Participants with an OW duration of 1-4 years, 5-8 years, and 8+ years were 0.96 (0.44-2.09), 1.20 (0.70-2.04) and 1.52 (1.22-1.90) times more likely to be high risk for OSA compared with those who were never OW (P for trend: 0.0002). These results suggest that childhood OW is associated with a high risk of OSA in middle age.

Associated Clinical Trials

May 26, 2000·Lydia A. Bazzano

References

Nov 1, 1982·The American Journal of Clinical Nutrition·J A BaeckeJ E Frijters
Mar 1, 1995·Journal of the American Dietetic Association·H R RockettG A Colditz
Dec 6, 1997·Preventive Medicine·H R RockettG A Colditz
May 6, 1999·American Journal of Respiratory and Critical Care Medicine·S RedlineG Graham
Oct 3, 1999·Annals of Internal Medicine·N C NetzerK P Strohl
Jun 3, 2006·American Journal of Epidemiology·Diane S LauderdaleKiang Liu
Aug 9, 2007·Sleep & Breathing = Schlaf & Atmung·Athanasios G KaditisGeorge A Syrogiannopoulos
Nov 21, 2007·Bulletin of the World Health Organization·Mercedes de OnisJonathan Siekmann
Nov 27, 2007·Journal of Sleep Research·Karen A WatersLouise A Baur
Aug 7, 2008·American Journal of Epidemiology·Stephen R Cole, Miguel A Hernán
Dec 23, 2008·Lancet·T Douglas Bradley, John S Floras
Oct 27, 2010·International Journal of Obesity : Journal of the International Association for the Study of Obesity·J J Reilly, J Kelly
Mar 31, 2012·Pediatric Obesity·A S AlbergaG P Kenny
Apr 17, 2013·American Journal of Epidemiology·Paul E PeppardKhin Mae Hla
Nov 20, 2013·Pediatrics·Thomas H IngeStephen R Daniels
Jan 18, 2014·Gerontology·Megan M KelseyKristen J Nadeau
Feb 27, 2014·JAMA : the Journal of the American Medical Association·Cynthia L OgdenKatherine M Flegal
May 21, 2014·American Journal of Preventive Medicine·Jennifer B Dowd, Anna Zajacova
Jun 13, 2014·Pediatric Obesity·R J Scharf, M D DeBoer

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Citations

Jul 4, 2017·Pediatric Pulmonology·Antonia BarcelóMónica de la Peña
Apr 28, 2018·Pediatric Obesity·D G IngramA K Adams
Aug 22, 2018·Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals·Sartaj KhuranaSudeep Bose
Oct 27, 2017·European Respiratory Review : an Official Journal of the European Respiratory Society·Maria R BonsignoreJosep M Montserrat
May 26, 2017·Applied Microbiology and Biotechnology·Kaiming ChenJianmin Fang
Jan 30, 2018·Annals of the New York Academy of Sciences·Stephanie T ChungSheela N Magge
Mar 30, 2017·Western Journal of Nursing Research·Elizabeth Anne BennettMelissa Ann Kalarchian

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