Childhood sexual abuse moderates genetic influences on age at first consensual sexual intercourse in women

Behavior Genetics
Mary WaldronN G Martin

Abstract

We examine interactive effects of childhood sexual abuse (CSA) on heritable variation in age at first consensual sexual intercourse in a young cohort of 3,350 female and 2,724 male Australian twins. Consistent with hypotheses, genetic influences explained little if any variation in age at first consensual sexual intercourse for female twins reporting CSA (CSA(+)), with shared environment explaining 73%. For female twins reporting no history of CSA (CSA(-)), 39% of variation in age at first consensual sexual intercourse was explained by genetic effects, with shared environment accounting for 30%. For male twins, significant interactive effects of CSA on genetic and environmental variation in age at first consensual sexual intercourse were not observed. Overall genetic influences explained 51% of variation in age at first consensual sexual intercourse for male twins, with shared environment accounting for 8%. For both female and male twins, results from models that included conduct disorder as a covariate were near identical to results from models without conduct disorder.

References

Jul 1, 1978·Archives of General Psychiatry·J Endicott, R L Spitzer
Aug 1, 1978·The Journal of Nervous and Mental Disease·W CoryellT Reich
Aug 11, 1992·Archives of General Psychiatry·J B WilliamsB Rounsaville
Jan 1, 1990·Acta geneticae medicae et gemellologiae·S OokiK Hayakawa
Jan 1, 1989·Journal of Studies on Alcohol·A C HeathN G Martin
Jan 1, 1966·Acta Genetica Et Statistica Medica·R C Nichols, W C Bilbro
Jun 1, 1966·The Journal of Surgical Research·A Boba, S R Powers
Oct 1, 1994·Psychological Review·U Bronfenbrenner, S J Ceci
Oct 1, 1996·Journal of the American Academy of Child and Adolescent Psychiatry·D M FergussonL J Horwood
Jul 9, 1997·JAMA : the Journal of the American Medical Association·H L MacMillanD R Offord
Aug 1, 1997·Child Abuse & Neglect·D M FergussonM T Lynskey
Apr 29, 1998·Pediatrics·K FiscellaD Olds
Mar 3, 1999·Twin Research : the Official Journal of the International Society for Twin Studies·A C HeathN G Martin
Mar 13, 1999·Child Abuse & Neglect·G E WyattJ V Carmona
Mar 19, 1999·Journal of Biosocial Science·W B MillerD E Comings
Jan 1, 2000·Addiction·M HesselbrockV Hesselbrock
Oct 23, 2001·Twin Research : the Official Journal of the International Society for Twin Studies·A C HeathN G Martin
Dec 1, 2001·Journal of Abnormal Psychology·D M DickM Koskenvuo
Aug 6, 2002·Science·Avshalom CaspiRichie Poulton
Nov 20, 2002·American Journal of Health Behavior·Douglas Kirby
Feb 8, 2003·Twin Research : the Official Journal of the International Society for Twin Studies·Shaun Purcell
Oct 21, 2003·Journal of the American Academy of Child and Adolescent Psychiatry·Helen A BergenLeigh Roeger
Nov 25, 2003·Psychological Science·Eric TurkheimerIrving I Gottesman
Feb 24, 2006·Journal of Child Psychology and Psychiatry, and Allied Disciplines·Michael RutterAvshalom Caspi
Jul 21, 2006·Psychological Medicine·Elliot C NelsonNicholas G Martin

❮ Previous
Next ❯

Citations

Aug 6, 2009·Psychological Medicine·M D FriesenD M Fergusson
Sep 20, 2016·Current Addiction Reports·Ryan BogdanArpana Agrawal

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Twin Research and Human Genetics : the Official Journal of the International Society for Twin Studies
Mary WaldronN G Martin
Archives of Sexual Behavior
Michael J LyonsMing T Tsuang
Health Psychology : Official Journal of the Division of Health Psychology, American Psychological Association
Brian MustanskiRichard J Rose
© 2021 Meta ULC. All rights reserved