Childhood trauma and childhood urbanicity in relation to psychotic disorder

Social Psychiatry and Psychiatric Epidemiology
Aleida FrissenGROUP Investigators

Abstract

Urban upbringing and childhood trauma are both associated with psychotic disorders. However, the association between childhood urbanicity and childhood trauma in psychosis is poorly understood. The urban environment could occasion a background of social adversity against which any effect of childhood trauma increases. Also, any impact of the urban environment on likelihood of exposure to childhood trauma could be stronger in children who later develop psychotic disorder. The aim of this study was twofold: (1) to investigate whether childhood urbanicity moderates the effect of childhood trauma, in a model predicting psychotic disorder; (2) to investigate whether there is an association between the urban environment and childhood trauma and whether this is moderated by genetic liability for psychotic disorder. Patients with a diagnosis of non-affective psychotic disorder (n = 1119) and 589 healthy controls from the Netherlands and Belgium were studied. Childhood trauma was assessed with the Dutch version of the Childhood Trauma Questionnaire Short Form. Urban exposure was defined at four levels, considering the population density, using data from Statistics Netherlands and the equivalent database in Belgium. There was a significa...Continue Reading

References

Jun 1, 1990·Archives of General Psychiatry·J K WingN Sartorius
Oct 1, 1995·Child Development·C J CoultonJ Chow
Mar 1, 1997·Journal of the American Academy of Child and Adolescent Psychiatry·D P BernsteinL Handelsman
Oct 24, 1997·Psychological Review·E F Walker, D Diforio
Dec 22, 1999·Child Abuse & Neglect·C J CoultonM Su
Feb 7, 2001·The British Journal of Psychiatry : the Journal of Mental Science·J van OsP Delespaul
Aug 5, 2000·JAMA : the Journal of the American Medical Association·C HeimC B Nemeroff
Dec 20, 2000·Schizophrenia Research·C R BlylerR W Buchanan
Dec 26, 2001·Archives of General Psychiatry·C B Pedersen, P B Mortensen
Jul 31, 2002·Child Development·Rosario Ceballo, Vonnie C McLoyd
Dec 17, 2003·Acta Psychiatrica Scandinavica·I JanssenJ van Os
Sep 2, 2004·The British Journal of Psychiatry : the Journal of Mental Science·Paul E BebbingtonHoward Meltzer
Sep 10, 2005·Schizophrenia Bulletin·Lydia Krabbendam, Jim van Os
Jun 3, 2006·Pediatrics·Adam J Zolotor, Desmond K Runyan
Aug 2, 2007·The British Journal of Psychiatry : the Journal of Mental Science·Benoit BediouImane Tazi
Jan 19, 2008·The British Journal of Psychiatry. Supplement·Jean-Paul Selten, Elizabeth Cantor-Graae
Aug 2, 2008·Epidemiologic Reviews·Dana MarchEzra Susser
Mar 31, 2009·Schizophrenia Bulletin·Christian G KohlerPaul J Moberg
Sep 25, 2009·Schizophrenia Bulletin·Helen L FisherCraig Morgan
Aug 7, 2010·Progress in Neuro-psychopharmacology & Biological Psychiatry·Ganesan VenkatasubramanianBangalore N Gangadhar
Oct 6, 2010·Archives of General Psychiatry·UNKNOWN Genetic Risk and Outcome in Psychosis (GROUP) Investigators
Feb 5, 2013·Psychiatry Research·Marie-Audrey LavoieAmélie M Achim
Mar 4, 2014·Psychiatry Research·Christian G KohlerMonica E Calkins

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Citations

Sep 9, 2015·Schizophrenia Research and Treatment·Ravi Philip Rajkumar
Feb 17, 2018·Revista brasileira de psiquiatria : orgão oficial da Associação Brasileira de Psiquiatria, Asociación Psiquiátrica de la América Latina·Thiago M FidalgoSílvia S Martins
Mar 30, 2018·Schizophrenia Research and Treatment·Luigi Grillo
Jan 30, 2019·Current Opinion in Psychiatry·Dusica Lecic-Tosevski
Jun 19, 2019·Social Psychiatry and Psychiatric Epidemiology·Florentina M E PinckaersMarjan Drukker
Aug 8, 2019·Early Intervention in Psychiatry·Lilith Abrahamyan EmpsonPhilippe Conus
Dec 15, 2020·L'Encéphale·C AlexandreF Schürhoff
May 4, 2020·Psychiatry Research·Tyler M MooreRaquel E Gur
Jun 15, 2021·Frontiers in Psychiatry·Lotta-Katrin PriesSinan Guloksuz

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