Children with Functional Nausea-Comorbidities outside the Gastrointestinal Tract.

The Journal of Pediatrics
Sally E TarbellJohn E Fortunato

Abstract

To detail common comorbidities and procedures performed to evaluate functional nausea in children. In total, 63 children age 7-18 years seen in a tertiary care pediatric clinic who met Rome IV criteria for functional nausea prospectively completed an Intake Questionnaire, the Pediatric and Parent-Proxy PROMIS-25 Profile v 2.0, the Pediatric and Parent-Proxy Pediatric Sleep Disturbance-Short Form 4a, and the COMPASS 31 orthostatic intolerance scale to assess comorbidities. Medical records were reviewed for diagnostic tests performed to evaluate nausea and for additional comorbidities. Summary statistics were used to determine the most common comorbidities and diagnostic yield of the procedures. Intraclass correlation coefficients assessed agreement between parent and child reports on the PROMIS scales. Patients with functional nausea experienced multisystem comorbidities. A majority reported abdominal pain, headache, orthostatic intolerance, fatigue, disturbed sleep, anxiety, constipation, allergies, and vomiting. Agreement between parent-proxy and child report of symptoms on PROMIS scales was good to excellent (intraclass correlation coefficients = .78-.83; all P < .001). Patients underwent extensive diagnostic testing: 96 endo...Continue Reading

Citations

Feb 15, 2021·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Natalie V HoffmannJohn E Fortunato
Feb 20, 2021·Journal of Pediatric Gastroenterology and Nutrition·Sharon WolfsonBruno P Chumpitazi
Jun 12, 2021·Autism Research : Official Journal of the International Society for Autism Research·Oscar W H WongPatrick W L Leung

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