Chinese metabolic syndrome risk score

Southern Medical Journal
Fone-Ching HsiaoDee Pei

Abstract

The metabolic syndrome (MetS) was first proposed to predict the occurrence of cardiovascular disease and type 2 diabetes. However, it is difficult to identify subjects with MetS early. No previous studies designed to develop a predictive model for MetS in the Chinese population exists; this study was designed to fill that gap. A middle-aged Chinese cohort of 198 men and 154 women were followed for two years. The binary logistic regression and receiver operation characteristic (ROC) curve were used to develop a predictive model for the future development of MetS. Over two years of follow up, 30 of the 352 subjects (8.52%) without MetS at baseline subsequently developed MetS. Triglycerides (TG) had the highest area under the curve (AUC), while diastolic blood pressure had the lowest. In order to increase the prediction power, MetS components were arranged in the ROC model according to their AUC. After adding waist circumference (WC) to TG (model 1), the AUC was significantly higher than for TG alone. Adding other components into the model did not increase the AUC significantly. A risk score cutoff (0.078) was selected for the best predictive power of model 1 (sensitivity of 76.7%, specificity of 63.4%, with AUC of 76.8%). These r...Continue Reading

References

Nov 1, 1988·Diabetes/metabolism Reviews·G M Reaven, Y D Chen
Jun 27, 1998·JAMA : the Journal of the American Medical Association·B LamarcheJ P Després
Mar 27, 2001·BMJ : British Medical Journal·J P DesprésD Prud'homme
May 23, 2001·JAMA : the Journal of the American Medical Association·UNKNOWN Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults
Jan 9, 2004·Endocrinology and Metabolism Clinics of North America·Barbara V HowardDavid C Robbins
May 5, 2004·Hypertension·Mohammed F SaadSteven M Haffner
Mar 29, 2005·Diabetes Care·Robert RatnerUNKNOWN Diabetes Prevention Program Research Group
Apr 20, 2005·Annals of Internal Medicine·Trevor J OrchardUNKNOWN Diabetes Prevention Program Research Group
May 18, 2005·Endocrine Reviews·Takashi Kadowaki, Toshimasa Yamauchi
Jul 22, 2005·Endocrine·T Rajendra Kumar
Jul 22, 2005·Endocrine·Robert K Campbell
Nov 25, 2005·Diabetes & Vascular Disease Research : Official Journal of the International Society of Diabetes and Vascular Disease·Timo SaaristoJaakko Tuomilehto
Jul 11, 2006·The Journal of Clinical Investigation·Steven E ShoelsonAllison B Goldfine
Aug 23, 2006·Diabetic Medicine : a Journal of the British Diabetic Association·P E Heldgaard, S J Griffin
Dec 15, 2006·Nature·Jean-Pierre Després, Isabelle Lemieux
Mar 1, 2007·Diabetes·Abbas DehghanJacqueline C M Witteman
Apr 11, 2007·CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne·George YuanRobert A Hegele

❮ Previous
Next ❯

Citations

May 26, 2010·Clinics in Geriatric Medicine·Alan Sinclair, Adie Viljoen
Nov 1, 2018·PloS One·Jeanine M Van AncumAndrea B Maier
Dec 29, 2020·Diabetes, Metabolic Syndrome and Obesity : Targets and Therapy·Hui ZhangZhihong Ye
May 28, 2021·Diabetes, Metabolic Syndrome and Obesity : Targets and Therapy·Hui ZhangZhihong Ye

❮ Previous
Next ❯

Related Concepts

Related Feeds

CV Disorders & Type 2 Diabetes

This feed focuses on the association of cardiovascular diseases in patients with type 2 diabetes.

© 2021 Meta ULC. All rights reserved