Chinese version of Montreal Cognitive Assessment Basic for discrimination among different severities of Alzheimer's disease

Neuropsychiatric Disease and Treatment
Lin HuangQi-Hao Guo

Abstract

To find out whether the Chinese version of Montreal Cognitive Assessment Basic (MoCA-BC) and its subtests could be applied in discrimination among cognitively normal controls (NC), mild cognitive impairment (MCI), mild and moderate Alzheimer's Disease (AD), and furthermore, to determine the optimal cutoffs most sensitive to distinguish between them. A cross-sectional validation study. Huashan Hospital, Shanghai, China. There was a total of 1,969 participants: individuals with MCI (n=663), mild (n=345), moderate (n=441) AD, and cognitively NC (n=520) were recruited from the Memory Clinic, Huashan Hospital, Shanghai, China. Baseline MoCA-BC scores were collected from firsthand data. Two subtests were calculated from MoCA-BC: the Memory Index Score of MoCA-BC (MoCA-BC-MIS) and the Non-memory Index Score of MoCA-BC (MoCA-BC-NM). MoCA-BC was an effective cognitive tool to discriminate among NC, MCI, mild and moderate AD in the Chinese elderly across all education groups, implying that it was efficient not only for detecting MCI, but for different severities of AD as well. For MCI screening, the total score of MoCA-BC (MoCA-BC-T) and MoCA-BC-MIS had similar high sensitivity and specificity. For discrimination among MCI, mild and mode...Continue Reading

Citations

Mar 29, 2019·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·Lin DongBrian H May
Jun 27, 2020·Annals of Clinical and Translational Neurology·Lixiao HaoYing Han
Nov 18, 2020·Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists·Xin ZhaoJoseph H R Maes
Aug 11, 2021·Journal of the International Neuropsychological Society : JINS·Wei Gabriel QiYue Hong

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Software Mentioned

MIS
NM
MoCA
SPSS
Medcalc
BC

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