PMID: 3745873Sep 1, 1986Paper

Chitin synthesis in zygotes of Ascaris suum

Journal of Helminthology
P DubinskýE Ossikovski

Abstract

In Ascaris suum chitin is formed in the zygote immediately after oocyte fertilization, and its synthesis is completed in the eggs from the distal half of the uterus. Incorporation of radiocarbon [14C] glucose into chitin of the eggshell was 40-fold higher than incorporation of [14C] glucosamine. The same rank order also holds for the incorporation of label from these isotopes into the glycogen of the ovaries. A large part of the radiolabel was incorporated first into oocyte glycogen and only after fertilization was it incorporated into eggshell chitin. Actinomycin D inhibited chitin synthesis in the eggs from the distal half of the uterus and it significantly reduced incorporation of radiocarbon from glucose into chitin.

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Citations

Feb 13, 2001·Molecular and Biochemical Parasitology·M T HarrisJ A Fuhrman
Jan 1, 1990·Parasitology Research·K D SpindlerM Londershausen
May 5, 2005·Molecular and Biochemical Parasitology·Jeremy M FosterClotilde K S Carlow
Sep 21, 2000·Memórias do Instituto Oswaldo Cruz·J SchotteliusS C Gonçalves da Costa

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