Chito-oligosaccharide reduces diarrhea incidence and attenuates the immune response of weaned pigs challenged with Escherichia coli K88

Journal of Animal Science
P LiuS W Kim

Abstract

Seventy-two barrows (Landrace × Large White, initial BW of 4.9 ± 0.3 kg and 17 ± 3 d old) were used to determine if dietary chito-oligosaccharides can replace antibiotics as a means to reduce signs associated with infection in weaned pigs challenged with Escherichia coli. Pigs were assigned to 1 of 4 treatments in a randomized complete block design using 6 pens per treatment with 3 pigs per pen. The treatments consisted of pigs fed the unsupplemented corn-soybean meal diet challenged or unchallenged with E. coli K88 and pigs fed the same diet supplemented with 160 mg of chito-oligosaccharides or 100 mg of cyadox/kg and challenged with E. coli K88. On d 7, 1 group of pigs fed the unsupplemented diet, as well as all pigs fed diets containing chito-oligosaccharides or cyadox, were orally dosed with 30 mL of an alkaline broth containing E. coli K88. Another group of pigs fed the unsupplemented diet was orally dosed with 30 mL of sterilized alkaline broth. Fecal consistency was visually assessed each morning from d 7 to 14. Blood samples were collected at 0, 24, 48, and 168 h postinfection. On d 14 postchallenge, all pigs were killed to evaluate intestinal morphology and determine E. coli concentrations in the intestine. During the ...Continue Reading

References

Aug 1, 1977·The American Journal of Clinical Nutrition·R W Wannemacher
Jun 1, 1995·The Journal of Nutrition·G R Gibson, M B Roberfroid
May 1, 1997·Journal of Animal Science·R W Johnson
Dec 19, 1998·Journal of Veterinary Internal Medicine·M L CebraM J Fettman
Oct 24, 2000·International Journal of Medical Microbiology : IJMM·P Klemm, M A Schembri
Oct 30, 2001·The Proceedings of the Nutrition Society·K E Bach Knudsen
Apr 25, 2002·Proceedings of the National Academy of Sciences of the United States of America·David L SmithJ Glenn Morris
Nov 5, 2002·Journal of Animal Science·L A WhiteM D Lindemann
Feb 10, 2006·Veterinary Microbiology·Gerda M JensenKristian Møller
Feb 19, 2008·The Journal of Nutritional Biochemistry·Peng SunFenglai Wang

❮ Previous
Next ❯

Citations

Feb 23, 2013·Journal of Agricultural and Food Chemistry·Maria I Quintero-VillegasRobert W Hutkins
Sep 17, 2013·Journal of Animal Science and Biotechnology·Philip A Thacker
Apr 18, 2014·Animal : an International Journal of Animal Bioscience·V BontempoA Agazzi
Oct 2, 2012·Annual Review of Entomology·Arnold van Huis
Jul 22, 2014·Journal of Animal Physiology and Animal Nutrition·S SwiatkiewiczD Jozefiak
Nov 8, 2018·The British Journal of Nutrition·Lydia C GarasElizabeth A Maga
May 28, 2019·Frontiers in Physiology·Guiping GuanHongbing Wang
Jan 10, 2020·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Wen XiongZili Wang
Jun 19, 2019·Journal of Animal Science and Biotechnology·Diana LuisePaolo Trevisi
Nov 26, 2020·Acta Cirúrgica Brasileira·Nan-Nan XueHuai Xiao
Dec 20, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Saravut Satitsri, Chatchai Muanprasat
Mar 2, 2021·Frontiers in Veterinary Science·Lan ZhengSung Woo Kim

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Antifungals (ASM)

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.