Chitosan based-nanoparticles and nanocapsules: Overview, physicochemical features, applications of a nanofibrous scaffold, and bioprinting.

International Journal of Biological Macromolecules
Kamel R ShoueirMaged El-Kemary

Abstract

Recent advancements in the synthesis, properties, and applications of chitosan as the second after cellulose available biopolymer in nature were discussed in this review. A general overview of processing and production procedures from A to Z was highlighted. Chitosan exists in three polymorphic forms which differ in degree of crystallinity (α, β, and γ). Thus, the degree of deacetylation, crystallinity, surface area, and molecular mass significantly affect most applications. Otherwise, the synthesis of chitosan nanofibers is suffering from many drawbacks that were recently treated by co-electrospun with other polymers such as polyvinyl alcohol (PVA), polyethylene oxide (PEO), and polycaprolactone (PCL). Ultimately, this review focuses on the area of new trend utilization of chitosan nanoparticles as nanospheres and nanocapsules, in cartilage and bone regenerative medicine. Owing to its biocompatibility, bioavailability, biodegradability, and costless synthesis, chitosan is a promising biopolymeric structure for water remediation, drug delivery, antimicrobials, and tissue engineering.

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Citations

Apr 4, 2021·International Journal of Molecular Sciences·Giuseppina AdilettaMilena Petriccione
May 1, 2021·Pharmaceutics·Andreea Teodora IacobLenuta Profire
Jun 3, 2021·Biomolecules·Mohamad Hesam ShahrajabianSpyridon A Petropoulos
Jul 2, 2021·International Journal of Biological Macromolecules·Hani Ababneh, B H Hameed
Aug 2, 2021·Methods : a Companion to Methods in Enzymology·Ana Luiza LimaGuilherme M Gelfuso
Aug 14, 2021·Beilstein Journal of Organic Chemistry·Giulio FittolaniMartina Delbianco
Aug 28, 2021·International Journal of Biological Macromolecules·Sarah I OthmanRehab Abdelmonem
Sep 11, 2021·International Journal of Molecular Sciences·Veronika Mikušová, Peter Mikuš

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