Chlamydia trachomatis and invasive cervical cancer: a pooled analysis of the IARC multicentric case-control study

International Journal of Cancer. Journal International Du Cancer
Jennifer S SmithIARC multicentric case-control study

Abstract

To determine whether Chlamydia trachomatis infection is consistently associated with an increased risk of invasive cervical carcinoma (ICC) after accounting for the strong effect of human papillomavirus (HPV) infection, a case-control study of 1,238 cases of ICC and 1,100 control women from 7 countries was carried out (hospital-based studies in Thailand, the Philippines, Morocco, Peru, Brazil and population-based studies in Colombia and Spain, all coordinated by the International Agency for Research on Cancer, Lyon, France). C. trachomatis serum antibody detection was made by means of a microfluorescence assay. Among HPV DNA-positive cases and controls, the risk of squamous cell ICC was elevated in C. trachomatis seropositive women (OR = 1.8; 95% CI = 1.2-2.7) after adjustment for age, center, oral contraceptive use, history of Pap smears, number of full-term pregnancies and herpes simplex virus 2 seropositivity. The effect of C. trachomatis seropositivity on squamous cell ICC risk increased with increasing C. trachomatis antibody titers and was higher in women under 55 years of age. C. trachomatis antibodies were not associated with adeno- or adenosquamous cell carcinoma (OR = 1.0; 95% CI = 0.53-1.9) in HPV DNA-positive women....Continue Reading

References

Nov 11, 1992·International Journal of Cancer. Journal International Du Cancer·N MuñozN Ascunce
May 1, 1986·Journal of Clinical Microbiology·M PuolakkainenJ Paavonen
Apr 20, 1994·Journal of the National Cancer Institute·A EkbomJ F Fraumeni
Jan 1, 1994·British Journal of Cancer·J Eluf-NetoJ M Walboomers
Feb 1, 1994·International Journal of Cancer. Journal International Du Cancer·S de SanjoséM Gili
May 1, 1997·The Journal of Infectious Diseases·R W PeelingR C Brunham
Jan 15, 1998·Journal of the National Cancer Institute·C NgelangelJ M Walboomers
Jan 15, 1998·Journal of the National Cancer Institute·S ChichareonJ M Walboomers
Feb 18, 1998·International Journal of Cancer. Journal International Du Cancer·N ChaoukiJ M Walboomers
Apr 17, 1998·Cancer Metastasis Reviews·E Felley-Bosco
Jun 10, 1998·Human Reproduction·J A LandV J Goossens
Jun 22, 1999·Human Reproduction·B W MolP M Bossuyt
Aug 19, 1999·The Journal of Pathology·J M WalboomersN Muñoz
Dec 10, 1999·International Journal of Cancer. Journal International Du Cancer·P KoskelaJ Paavonen
Jan 10, 2001·JAMA : the Journal of the American Medical Association·T AnttilaJ Paavonen
Apr 13, 2001·JAMA : the Journal of the American Medical Association·S A Morré, J M Ossewaarde
Oct 11, 2001·British Journal of Cancer·C SantosE Caceres
Apr 12, 2002·Lancet·Victor MorenoUNKNOWN International Agency for Research on Cancer. Multicentric Cervical Cancer Study Group
Apr 12, 2002·Lancet·Nubia MuñozUNKNOWN International Agency for Research on Cancer. Multicentric Cervical Cancer Study Group
Sep 5, 2002·International Journal of Cancer. Journal International Du Cancer·Keng-Ling WallinJoakim Dillner

❮ Previous
Next ❯

Citations

Nov 26, 2002·Virus Research·Xavier CastellsaguéNubia Muñoz
Nov 26, 2002·Virus Research·Martyn Plummer, Silvia Franceschi
May 15, 2007·The New England Journal of Medicine·Gypsyamber D'SouzaMaura L Gillison
Apr 12, 2012·Genetic Testing and Molecular Biomarkers·Asia AsiafSyed Hussain Mir
Mar 2, 2006·Journal of the National Cancer Institute·Xavier CastellsaguéUNKNOWN International Agency for Research on Cancer Multicenter Cervical Cancer Study Group
Nov 26, 2010·Journal of the National Cancer Institute·Mahboobeh SafaeianRobert D Burk
May 1, 2008·Sexually Transmitted Diseases·Carolina PorrasUNKNOWN Costa Rica HPV Vaccine Trial (CVT) Group
Oct 24, 2009·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·Alp UsubütünFrancesc Xavier Bosch
Oct 12, 2010·Clinical Microbiology Reviews·Alicia H Chang, Julie Parsonnet
Oct 26, 2007·Journal of Clinical Microbiology·Koen QuintUNKNOWN Costa Rican Vaccine Trial Group
Mar 26, 2009·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Zoe R EdelsteinLaura A Koutsky
Aug 11, 2010·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Anna-Barbara MoscickiStephen Shiboski
Feb 17, 2009·BMC Infectious Diseases·Rosita VerteramoAnna Marta Degener
Jun 28, 2011·Infectious Agents and Cancer·Michael OdidaElisabete Weiderpass
Jun 4, 2010·Drugs·Suzanne M Garland, Jennifer S Smith
Apr 24, 2012·Croatian Medical Journal·Iva KelavaAriana Znaor
Nov 4, 2010·Indian Journal of Pathology & Microbiology·Akbar SafaeiNegar Azarpira
Dec 19, 2013·Archives of Gynecology and Obstetrics·Jani SilvaRui Medeiros
Jun 4, 2014·Spatial and Spatio-temporal Epidemiology·Erik J NelsonShalini L Kulasingam
Nov 14, 2014·Nature Communications·Erik GonzálezThomas F Meyer
Feb 28, 2007·Leukemia & Lymphoma·Elías GraciaFrancesco Bertoni
Oct 30, 2012·The Journal of Infection·Carol ChelimoJ Mark Elwood
May 7, 2011·Enfermedades infecciosas y microbiología clínica·Manuel ParraEstrella Martín-Mazuelos
Jul 17, 2015·Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine·Na Hee HaHae Ryoun Park
Sep 2, 2008·Gynecologic Oncology·Xavier Castellsagué
Dec 22, 2015·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Katrin HaeusslerGianluca Baio
Sep 13, 2008·La Presse médicale·Nubia Muñoz, Anne-Carole Jacquard
Sep 23, 2008·Critical Reviews in Oncology/hematology·Catherine de Martel, Silvia Franceschi
Sep 11, 2007·Lancet·Mark SchiffmanSholom Wacholder
Jun 5, 2007·Current Problems in Cancer·Aletha Y AkersJennifer S Smith
Jun 19, 2007·Cytopathology : Official Journal of the British Society for Clinical Cytology·E N PolitiH Koutselini

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