Chlamydia trachomatis Incidence Using Self-Reports and Serology by Gender, Age Period, and Sexual Behavior in a Birth Cohort

Sexually Transmitted Diseases
A Antoinette RighartsNigel P Dickson

Abstract

Although understanding chlamydia incidence assists prevention and control, analyses based on diagnosed infections may distort the findings. Therefore, we determined incidence and examined risks in a birth cohort based on self-reports and serology. Self-reported chlamydia and behavior data were collected from a cohort born in New Zealand in 1972/3 on several occasions to age 38 years. Sera drawn at ages 26, 32, and 38 years were tested for antibodies to Chlamydia trachomatis Pgp3 antigen using a recently developed assay, more sensitive in women (82.9%) than men (54.4%). Chlamydia incidence by age period (first coitus to age 26, 26-32, and 32-38 years) was calculated combining self-reports and serostatus and risk factors investigated by Poisson regression. By age 38 years, 32.7% of women and 20.9% of men had seroconverted or self-reported a diagnosis. The highest incidence rate was to age 26, 32.7 and 18.4 years per 1000 person-years for women and men, respectively. Incidence rates increased substantially with increasing number of sexual partners. After adjusting age period incidence rates for partner numbers, a relationship with age was not detected until 32 to 38 years, and then only for women. Chlamydia was common in this coho...Continue Reading

References

Jun 13, 2001·Sexually Transmitted Infections·C A Sabin, A N Phillips
Feb 8, 2008·Sexually Transmitted Infections·Anne M Johnson, Paddy Horner
Mar 29, 2008·Sexually Transmitted Infections·Nicola Low
Jul 21, 2009·Sexually Transmitted Diseases·Christina B HosenfeldHeidi M Bauer
Nov 26, 2009·The Journal of Infectious Diseases·Byron E BatteigerJ Dennis Fortenberry
Jun 14, 2013·Epidemiology and Infection·M J PriceP J Horner
Dec 18, 2013·Sexually Transmitted Infections·Nigel DicksonAnthony L Cunningham
Jan 8, 2015·Sexually Transmitted Infections·Hammad AliUNKNOWN Australian chlamydia incidence estimation group
Apr 4, 2015·Social Psychiatry and Psychiatric Epidemiology·Richie PoultonPhil A Silva

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Citations

Jun 22, 2018·Sexually Transmitted Infections·Janneke C M HeijneBirgit H B van Benthem
May 30, 2021·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Gloria E AnyalechiKyle T Bernstein

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