Chlamydiales in guinea-pigs and their zoonotic potential

Journal of Veterinary Medicine. A, Physiology, Pathology, Clinical Medicine
L Lutz-WohlgrothL Vaughan

Abstract

The aim was to detect and characterize chlamydial infections in guinea-pigs (GP) with ocular disease, study their pathogenicity and zoonotic potential and to test for the presence of Acanthamoebae spp. in GP eyes and to investigate whether they could act as vectors for Chlamydia-like organisms. Overall 126 GP, of which 77 were symptomatic, were screened by clinical examination, cytology, gross pathology, histology, immunohistochemistry, polymerase chain reaction (PCR) and bacteriology. A new Chlamydiaceae-specific intergenic spacer rRNA gene PCR, designed to amplify this segment linking the 16S and 23S regions, was performed. DNA samples were also received from one owner including samples of his cat and rabbit. Guinea-pigs: 48 of 75 symptomatic, but only 11 of 48 asymptomatic GP were positive by PCR for Chlamydophila caviae guinea-pig inclusion conjunctivitis (GPIC) (P < 0.0001). Eighteen of 75 or 15/48, respectively, were positive for DNA from Chlamydia-like organisms. Acanthamoebae-DNA could be found in two GP, of which one was symptomatic. Owner, cat and rabbit: Samples of all three species were positive by PCR for C. caviae GPIC and the owner's one-day disposable contact lenses showed a positive PCR result for the Chlamydia...Continue Reading

References

Apr 1, 1989·Laboratory Animals·B J DeebS P Wang
Nov 1, 1985·Infection·A J Martinez, K Janitschke
Oct 1, 1986·Proceedings of the National Academy of Sciences of the United States of America·N G WatkinsH D Caldwell
Oct 1, 1987·American Journal of Infection Control·N M WatkinsD N MacKay
Apr 1, 1966·The Journal of Infectious Diseases·F B GordonH R Dressler
May 1, 1967·American Journal of Ophthalmology·K F Meyer
Jul 1, 1967·American Journal of Ophthalmology·J J KazdanM Okumoto
Mar 1, 1983·The British Veterinary Journal·F W Johnson
Jul 1, 1981·Sexually Transmitted Diseases·R G RankA L Barron
Sep 1, 1997·Nucleic Acids Research·S F AltschulD J Lipman
Feb 13, 1999·Journal of Clinical Microbiology·K D EverettA A Andersen
Feb 15, 2001·American Journal of Industrial Medicine·E Melbostad, W Eduard
Feb 24, 2001·International Journal of Systematic and Evolutionary Microbiology·R M Bush, K D Everett
Dec 19, 2001·Emerging Infectious Diseases·T J MarrieUNKNOWN Canadian Community-Acquired Pneumonia Study Group
May 25, 2002·Emerging Infectious Diseases·Gilbert Greub, Didier Raoult
Jul 2, 2003·Journal of Comparative Pathology·D Longbottom, L J Coulter
Jul 16, 2003·Annals of the New York Academy of Sciences·Gilbert GreubClaude Martin
May 1, 1964·Stain Technology·D F GIMENEZ
Nov 19, 2003·American Journal of Veterinary Research·Wolf von BomhardAndreas Pospischil

❮ Previous
Next ❯

Citations

Nov 22, 2011·Transboundary and Emerging Diseases·N Wheelhouse, D Longbottom
Jul 19, 2011·Applied and Environmental Microbiology·Steen NordentoftKarl Pedersen
Oct 14, 2009·PloS One·Fabienne PaumetJames E Rothman
Jan 1, 2009·Emerging Infectious Diseases·David BaudGilbert Greub
May 10, 2011·Veterinary Microbiology·Nick WheelhouseDavid Longbottom
Apr 7, 2009·Veterinary Microbiology·Annie Rodolakis, Khalil Yousef Mohamad
Nov 7, 2008·Veterinary Microbiology·Konrad SachseDavid Longbottom
Oct 24, 2008·Veterinary Microbiology·A PolkinghorneL Vaughan
Feb 4, 2014·Journal of Wildlife Diseases·Sarah StephanNicole Borel
Jul 14, 2010·Veterinary Ophthalmology·Marianne RichterGilbert Greub
Sep 25, 2010·Veterinary Ophthalmology·David Williams, Ann Sullivan
May 3, 2006·Veterinary Microbiology·K TeankumN Borel
Feb 18, 2009·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·G Greub
Jul 26, 2007·Journal of Veterinary Medicine. A, Physiology, Pathology, Clinical Medicine·A BeckerL Vaughan
Jan 10, 2018·Veterinary Pathology·Nicole BorelAndreas Pospischil
Jul 10, 2018·Vector Borne and Zoonotic Diseases·Rebecca van GrootveldMark G J de Boer
Nov 8, 2019·PloS One·Kimberly FilcekBarbara S Sixt
Feb 26, 2019·Frontiers in Veterinary Science·Javier Sánchez RomanoMorten Tryland
Feb 14, 2015·Euro Surveillance : Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin·E R HeddemaD Vanrompay
Sep 7, 2017·The New England Journal of Medicine·Bart P RamakersMirjam H A Hermans
May 30, 2019·Microorganisms·Heng Choon CheongWon Fen Wong

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2022 Meta ULC. All rights reserved