Chloral hydrate as a sedating agent for neurodiagnostic procedures in children.

The Cochrane Database of Systematic Reviews
Choong Yi FongNai Ming Lai

Abstract

Paediatric neurodiagnostic investigations, including brain neuroimaging and electroencephalography (EEG), play an important role in the assessment of neurodevelopmental disorders. The use of an appropriate sedative agent is important to ensure the successful completion of the neurodiagnostic procedures, particularly in children, who are usually unable to remain still throughout the procedure. To assess the effectiveness and adverse effects of chloral hydrate as a sedative agent for non-invasive neurodiagnostic procedures in children. We used the standard search strategy of the Cochrane Epilepsy Group. We searched MEDLINE (OVID SP) (1950 to July 2017), the Cochrane Central Register of Controlled Trials (CENTRAL) (the Cochrane Library, Issue 7, 2017), Embase (1980 to July 2017), and the Cochrane Epilepsy Group Specialized Register (via CENTRAL) using a combination of keywords and MeSH headings. We included randomised controlled trials that assessed chloral hydrate agent against other sedative agent(s), non-drug agent(s), or placebo for children undergoing non-invasive neurodiagnostic procedures. Two review authors independently assessed the studies for their eligibility, extracted data, and assessed risk of bias. Results were exp...Continue Reading

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Citations

Jul 12, 2019·Paediatric Drugs·Eytan KaplanElhanan Nahum
Mar 18, 2020·European Journal of Pediatrics·Amal HajjijKhalid Snoussi
May 28, 2019·Minerva anestesiologica·Keira P Mason, Neena Seth
May 11, 2021·Frontiers in Neurology·Mustafa Salimeen Abdelkareem SalimeenJian Yang
Aug 17, 2021·The Cochrane Database of Systematic Reviews·Choong Yi FongNai Ming Lai

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