PMID: 6408667Jan 1, 1983Paper

Chlordiazepoxide and ethanol additively reduce gustatory negative contrast

Psychopharmacology
H C Becker, C F Flaherty

Abstract

Negative contrast that occurs when rats are shifted from 32% to 4% sucrose has been shown to be reduced by chlordiazepoxide (CDP) and ethanol (ETOH). In a previous experiment, doses of 0.75 and 1.0 g/kg ETOH substantially reduced contrast while doses of 0.25 and 0.5 g/kg ETOH were much less effective. In this study, doses of 6 and 8 mg/kg CDP were shown to attenuate the negative contrast effect while smaller doses (2 and 4 mg/kg) influenced contrast to a lesser degree. Evidence for an additive effect of CDP and ETOH on contrast reduction was obtained when 4 mg/kg CDP and 0.5 g/kg ETOH were administered together.

References

Jul 27, 1978·Nature·J F TallmanD W Gallager
Jan 18, 1980·Science·J F TallmanD W Gallager
Jan 1, 1980·Psychopharmacology·C F FlahertyD Deptula
Jan 1, 1980·Psychopharmacology·C F Flaherty, C D Driscoll
Jan 1, 1982·Psychopharmacology·H C Becker, C F Flaherty

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Citations

Jan 1, 1987·Psychopharmacology·G A Rowan, C F Flaherty
Aug 1, 1987·Pharmacology, Biochemistry, and Behavior·C F FlahertyM K Demetrikopoulos
Aug 1, 1990·Pharmacology, Biochemistry, and Behavior·C F FlahertyG A Rowan
Oct 1, 1991·Pharmacology, Biochemistry, and Behavior·P S Grigson, C F Flaherty
May 1, 1992·Pharmacology, Biochemistry, and Behavior·C F FlahertyP S Grigson
Jan 1, 1986·Neuroscience and Biobehavioral Reviews·S O Cole
Jan 1, 1990·Pharmacology & Therapeutics·C F Flaherty
Apr 2, 2003·Pharmacology, Biochemistry, and Behavior·Ruey-Ming Liao, Feng-Jung Chuang
Feb 1, 1989·Journal of the American College of Nutrition·C F Flaherty, G A Rowan
Nov 8, 2015·Pharmacology, Biochemistry, and Behavior·Mariana PsyrdellisNadia Justel
Oct 24, 2013·Physiology & Behavior·Lidia ManzoCarmen Torres
Mar 13, 2015·Psychopharmacology·Yann PellouxDominique Duterte-Boucher
Sep 28, 2014·Neurobiology of Learning and Memory·Nadia JustelAlba Mustaca
Dec 3, 2014·Neuroscience and Biobehavioral Reviews·Mauricio R PapiniCarmen Torres
Dec 13, 2002·Behavioural Pharmacology·R F GennA G Phillips

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