Chlorinated benzene induction of hepatic porphyria

G P Carlson


1,4-Dichlorobenzene and 1,2,4-trichlorobenzene were compared with hexachlorobenzene which is known to cause porphyria. Although hexachlorobenzene administration resulted in a manyfold increase in liver porphyrin levels and urinary excretion of porphyrins, the lesser chlorinated compounds did not do so.


May 1, 1976·Toxicology and Applied Pharmacology·G P Carlson, R G Tardiff
Apr 1, 1970·Clinica Chimica Acta; International Journal of Clinical Chemistry·L C San Martin de VialeM Grinstein
Sep 1, 1972·The Biochemical Journal·C RajamanickamG Padmanaban
Dec 1, 1963·Biochemical Pharmacology·C RIMINGTON, G ZIEGLER


Oct 16, 2007·Journal of Toxicology and Environmental Health. Part B, Critical Reviews·Dallas B AronsonPatrick D Guiney
Apr 15, 1979·Experientia·G P Carlson
Jan 1, 1983·Drug and Chemical Toxicology·D P SasmoreJ S Johnson
Dec 1, 1994·Human & Experimental Toxicology·C den BestenP J van Bladeren

Related Concepts

Disorders of Porphyrin Metabolism
Rats, Laboratory
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