PMID: 9171092Jun 15, 1997Paper

Chloroplast endoribonuclease p54 involved in RNA 3'-end processing is regulated by phosphorylation and redox state

Nucleic Acids Research
K Liere, G Link

Abstract

Chloroplast RNA-binding protein p54 is an endoribonuclease required for 3'end-processing of plastid precursor transcripts. We find that purified p54 can serve as a phosphate acceptor for protein kinases in vitro. Both the processing and RNA-binding activities of p54 are enhanced by phosphorylation and decreased by dephosphorylation. In addition, the enzyme is activated by the oxidized form of glutathione and inhibited by the reduced form, whereas other redox reagents that were tested showed no effect. Kinase treatment of p54 prior to oxidation by glutathione resulted in highest levels of activation, suggesting that phosphorylation and redox state act together to control p54 activity in vitro and possibly also in vivo.

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Citations

Aug 18, 2000·Biochimie·R A MondeD B Stern
Jan 14, 2003·Trends in Plant Science·Thomas Pfannschmidt
Sep 11, 2002·The Plant Journal : for Cell and Molecular Biology·Dominique DrapierFrancis-André Wollman
May 26, 2010·Proceedings of the National Academy of Sciences of the United States of America·Masanori ShimizuHirokazu Kobayashi
Mar 11, 2003·Antioxidants & Redox Signaling·Gerhard Link
Mar 11, 2003·Antioxidants & Redox Signaling·Dwight Barnes, Stephen P Mayfield
May 14, 2005·Antioxidants & Redox Signaling·Thomas Pfannschmidt, Karsten Liere
Oct 18, 2002·Nucleic Acids Research·Sacha Baginsky, Wilhelm Gruissem
Sep 13, 2003·Plant Physiology·Rüdiger Hauschild, Antje von Schaewen
Nov 13, 2007·The Plant Journal : for Cell and Molecular Biology·Michel Goldschmidt-ClermontJean-David Rochaix
Mar 29, 2013·Wiley Interdisciplinary Reviews. RNA·Arnaud GermainDavid B Stern
Dec 10, 2009·Molecular Plant·Sacha Baginsky, Wilhelm Gruissem
Oct 20, 2000·The Journal of Biological Chemistry·T NakamuraM Sugita
Nov 25, 2004·The Journal of Biological Chemistry·Vidal FeyThomas Pfannschmidt
Feb 3, 2007·Journal of Proteome Research·Sacha BaginskyWilhelm Gruissem

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