Cholangiopancreatoscopy for targeted biopsies of the bile and pancreatic ducts

Gastrointestinal Endoscopy Clinics of North America
Shahzad Iqbal, Peter D Stevens

Abstract

Establishing a tissue diagnosis in patients with suspected pancreaticobiliary malignancies remains challenging. Endoscopic retrograde cholangiopancreatography (ERCP)-based sampling methods have been reviewed in a previous issue of this journal but, unfortunately, the diagnostic yield continues to be inadequate in a significant minority of patients. The availability and image quality of cholangioscopy and pancreatoscopy have advanced in the last few years and our ability to make a diagnosis on imaging alone is improving. However, a definitive diagnosis requires tissue; cholangiopancreatoscopy allows targeted biopsies of the epithelium of the biliary and pancreatic ducts. This article reviews the evidence that cholangioscopy- and pancreatoscopy-guided biopsies improves diagnostic yield over ERCP-based tissue sampling techniques.

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Citations

Nov 11, 2010·Journal of Clinical Gastroenterology·Caroline S LoeserPriya Jamidar
Oct 21, 2011·Journal of Clinical Gastroenterology·Frederick K ShiehPriya A Jamidar
Dec 2, 2014·Clinics in Liver Disease·Brian C Brauer, Raj J Shah
Jun 23, 2011·Digestive Diseases and Sciences·Jennifer ChennatIrving Waxman
May 12, 2012·Gastroenterology Research and Practice·Ioana SmithMichel Kahaleh
Apr 29, 2015·World Journal of Gastroenterology : WJG·Mohan RamchandaniChristopher Khor

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