PMID: 16641535Apr 28, 2006Paper

Cholecystitis caused by infiltration of immature myeloid cells: a case report

Journal of Nippon Medical School = Nippon Ika Daigaku Zasshi
Tetsuya ShimizuZenya Naito

Abstract

A 59-year-old man with myelodysplastic syndrome who was hospitalized for evaluation of fever and generalized fatigue had elevated levels of C-reactive protein and pancytopenia. A search for a site of infection and empiric treatment with antibiotics were unsuccessful. Over 5 to 6 weeks right upper quadrant pain and rebound tenderness developed. Sonographic Murphys sign was present. Computed tomography showed thickening of the gallbladder wall, and repeated ultrasonography demonstrated changes consistent with cholecystitis. Open cholecystectomy was performed as an emergency procedure. Macroscopically the resected gallbladder showed an edematous and thickened wall. Histopathologic examination revealed transmural infiltration by atypical mononuclear cells with distinct nuclei. The cells showed immunohistochemical staining for CD15, indicating myeloid lineage. By 10 days after surgery, counts of leukocytes and leukoblasts had markedly increased, reaching 36,700/microL and 76.0%, respectively. The blast crisis was thought to indicate progression from myelodysplastic syndrome to leukemia. The patient died of progressive disease 12 days after surgery. We have described a rare case of acute cholecystitis caused by infiltration of immatu...Continue Reading

References

Jan 1, 1992·Leukemia Research·G F Sanz, M A Sanz
Jul 1, 1988·American Journal of Surgery·E A VaughnW A Sterling
Dec 1, 1985·American Journal of Surgery·J A HawkinsE W Nelson
Oct 1, 1974·Cancer·S BjörnssonJ F Holland
Jan 1, 1993·AJR. American Journal of Roentgenology·D E FinlayD G Longley
Oct 1, 1998·Journal of Clinical Gastroenterology·Y BüyükaşikS Dündar
Apr 26, 2002·British Journal of Haematology·Marcus GorschlüterAxel Glasmacher
Jul 12, 2002·American Journal of Hematology·Stuart H BloomDale E Hammerschmidt
Jan 16, 2003·Leukemia Research·David P Steensma, Ayalew Tefferi

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