Cholera risk factors, Papua New Guinea, 2010

BMC Infectious Diseases
Alexander RosewellC Raina MacIntyre

Abstract

Cholera is newly emergent in Papua New Guinea but may soon become endemic. Identifying the risk factors for cholera provides evidence for targeted prevention and control measures. We conducted a hospital-based case-control study to identify cholera risk factors. Using stool culture as the standard, we evaluated a cholera point of care test in the field. 176 participants were recruited: 54 cases and 122 controls. Independent risk factors for cholera were: being over 20 years of age (aOR 2.5; 95%CI 1.1, 5.4), defecating in the open air (or river) (aOR 4.5; 95% CI 1.4, 14.4) and knowing someone who travelled to a cholera affected area (aOR 4.1; 95%CI 1.6, 10.7); while the availability of soap for handwashing at home was protective (aOR 0.41; 95%CI 0.19, 0.87). Those reporting access to a piped water distribution system in the home were twice as likely to report the availability of soap for handwashing. The sensitivity and specificity of the rapid test were 72% (95% CI 47-90) and 71% (95%CI 44-90%). Improving population access to the piped water distribution system and sanitation will likely reduce transmission by enabling enhanced hygiene and limiting the contamination of water sources. The One step V. cholerae O1/O139 Antigen Tes...Continue Reading

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Citations

Nov 6, 2013·Emerging Infectious Diseases·Alexander RosewellC Raina MacIntyre
Dec 10, 2013·Western Pacific Surveillance and Response Journal : WPSAR·Alexander RosewellAnthony Zwi
Nov 19, 2015·BMC Public Health·Dickson Shey NsaghaOdette Dzemo Kibu
May 18, 2016·Epidemiology and Health·Ghobad MoradiHojatollah Barati
Jul 4, 2018·The American Journal of Tropical Medicine and Hygiene·Marlene WolfeDaniele Lantagne
Apr 24, 2019·Epidemiology and Health·Fekri DureabOlaf Müller
Jul 26, 2019·Tropical Medicine & International Health : TM & IH·Matthew D PhelpsPeter K M Jensen
Nov 5, 2013·The Medical Journal of Australia·John J HallPilly Mapira
Aug 24, 2018·The Journal of Infectious Diseases·Aaron RichtermanLouise C Ivers

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