Cholesteatoma in children: histopathologic findings in middle ear ossicles

ORL; Journal for Oto-rhino-laryngology and Its Related Specialties
A QuarantaS Iurato

Abstract

Middle ear ossicles removed during ear surgery in 40 patients were examined in order to compare the histopathologic changes in children with those observed in adults. Bone resorption, mainly localized at the level of the periosteum and haversian canals in adults, was much more extensive in children. Replacement of bone by fibrous granulation tissue was observed in 60% of children's ossicles and in 27% of those belonging to adults. In children, extensive active resorptive osteitis of the ossicles was frequently associated with intensive round cell infiltration, which seems to play an important role in bone absorption and in the aggressiveness of cholesteatoma.

Citations

Apr 7, 2007·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Milan Stankovic
Jan 5, 2010·Experimental and Molecular Pathology·Mahmoud Rezk Abdelwahed HusseinEman E Abu-Dief
Jan 1, 2015·Acta Medica (Hradec Králové)·Lukáš ŠkoloudíkViktor Chrobok
Oct 18, 2013·Acta Oto-laryngologica·Lukas SkoloudikJan Laco

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