Cholesterol esterification and lipids in plasma and liver from newborn and young guinea pigs raised on milk and non-milk diet.

Nutrition and Metabolism
C A Drevon, K R Norum

Abstract

Plasma lecithin:cholesterol acyltransfer (LCAT), liver acyl-CoA:cholesterol acyltransfer (ACAT) and plasma and liver lipids were examined in newborn and young guinea pigs fed ordinary or a non-milk diet. LCAT in newborns was about 70% of the adult value, increased the first 3 days to values about three times the adult value, and decreased during the next 3 weeks to about adult value. Plasma lipids varied in a similar way. Liver ACAT in newborns was considerably higher than in adults. In young animals on non-milk diet the LCAT and ACAT were lower than in normally fed animals. LCAT was positively correlated to free cholesterol in plasma.

Citations

Dec 1, 1978·Journal of Steroid Biochemistry·J I Pedersen, K Saarem
Jan 1, 1979·Comparative Biochemistry and Physiology. B, Comparative Biochemistry·B H Dannevig, K R Norum
Jan 1, 1982·Comparative Biochemistry and Physiology. B, Comparative Biochemistry·B H Dannevig, K R Norum
Jan 1, 1983·Comparative Biochemistry and Physiology. B, Comparative Biochemistry·B H Dannevig, K R Norum
Dec 1, 1982·Proceedings of the National Academy of Sciences of the United States of America·R BlomhoffK R Norum
Jun 1, 1977·Metabolism: Clinical and Experimental·P BarterR J Havel
Jun 1, 1983·Atherosclerosis·D KritchevskyD M Klurfeld
Feb 1, 1979·European Journal of Clinical Investigation·K R NorumB Selbekk
Dec 1, 1982·European Journal of Clinical Investigation·P HelgerudK R Norum
Nov 1, 1978·Scandinavian Journal of Clinical and Laboratory Investigation·G NordbyK R Norum
Jan 1, 1978·Scandinavian Journal of Gastroenterology·B Beck, C A Drevon
Apr 1, 1981·Scandinavian Journal of Gastroenterology·K R NorumA C Lilljeqvist
Jan 1, 1977·Acta Pathologica Et Microbiologica Scandinavica. Section A, Pathology·C A Drevon, T Hovig
Nov 1, 1977·Acta Pathologica Et Microbiologica Scandinavica. Section A, Pathology·G NordbyK R Norum
Feb 1, 1981·Scandinavian Journal of Clinical and Laboratory Investigation·L OseT Berg
Dec 16, 1988·Biochimica Et Biophysica Acta·S K EricksonA Trentalance
Oct 21, 1976·Biochimica Et Biophysica Acta·G NordbyK R Norum
Jul 7, 1978·Biochimica Et Biophysica Acta·J I Pedersen, H K Godager
Jan 1, 1979·Progress in Lipid Research·A A SpectorT L Kaduce

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