Cholesterol masses in association with spinal cord infarction due to intervertebral disc emboli.

Acta Neuropathologica
I R GriffithsA C Palmer

Abstract

The clinical and autopsy findings are presented from three dogs with spinal cord infarction. At autopsy firm gritty masses and cystic areas were present within the spinal cord. The masses contained numerous cholesterol clefts, collagen and reticulin fibres and were accompanied by a macrophage, giant cell and lymphocytic response. The cholesterol masses were present mainly in white matter. The ventral spinal artery or its branches as well as pial arteries contained fibrillary masses often covered by endothelial cells. The staining characteristics of these emboli suggested that they were fibro-cartilagenous and probably derived from the intervertebral discs. It is assumed that the cholesterol masses were formed from myelin breakdown products within infarcted areas.

References

Apr 1, 1973·Journal of Comparative Pathology·I R Griffiths
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Jan 1, 1961·Neurology·J L NAIMANJ S PRICHARD
Jan 1, 1965·Journal of Neuropathology and Experimental Neurology·I FEIGINM ADACHI

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Citations

May 5, 2005·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Fredrik I GrünenfelderFrank Steffen
Dec 1, 1989·Journal of Neurosurgery·J R KestleW Kucharczyk
Jan 14, 1999·The American Journal of Forensic Medicine and Pathology·O M YousefM Kornfeld
Jul 1, 1986·Neuropathology and Applied Neurobiology·M Jeffrey, G A Wells

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