PMID: 8602715Mar 1, 1996Paper

Cholesterol screening in asymptomatic adults, revisited. Part 2

Annals of Internal Medicine
A M GarberS B Hulley

Abstract

To assess the role of serum lipid levels as screening tests in adults. Pooled analysis of clinical trials, supplemented by analysis of data from the Framingham Heart Study, to estimate the effect of cholesterol reduction in patient groups stratified by cardiac risk. Published randomized controlled trials of cholesterol reduction, meta-analyses of such trials, prospective cohort studies of the association between cholesterol levels and morbidity and death related to coronary heart disease, and cost-effectiveness analyses of cholesterol reduction. Two-stage logistic regression on cardiac risk factors and outcomes in the Framingham Heart Study. The first stage predicted the risk for death from coronary heart disease using standard risk factors but not cholesterol; the second stage predicted the risk for death from coronary heart disease and all causes as functions of age and cholesterol level, stratified by the risk predicted from the first stage. Randomized clinical trials show that cholesterol reduction confers survival benefits in patients with symptomatic coronary disease. In asymptomatic middle-aged men, who are at lower risk for death from coronary disease, cholesterol reduction prevents coronary disease but has not been sho...Continue Reading

Associated Clinical Trials

Citations

Sep 16, 1999·Clinical Cardiology·M J Budoff, B H Brundage
Jun 24, 2004·Current Treatment Options in Cardiovascular Medicine·William S. Weintraub
Mar 25, 1999·Clinica Chimica Acta; International Journal of Clinical Chemistry·A H WuT G Cole
Mar 11, 2000·Disease-a-month : DM·P R Liebson, E A Amsterdam
Dec 23, 1998·Survey of Ophthalmology·W C Stewart, J Osterman
Feb 25, 1998·Transplantation Proceedings·J P LashR Pollak
Jan 7, 1997·Journal of Health Economics·A M Garber, C E Phelps
Nov 21, 1998·Social Science & Medicine·M Berkwits
Apr 12, 2000·Journal of the American College of Cardiology·K O AkosahA Schaper
Apr 18, 2001·American Journal of Preventive Medicine·UNKNOWN US Preventive Services Task Force
Oct 29, 1998·American Journal of Preventive Medicine·S K DavisJ W Farquhar
Jul 23, 2002·Journal of General Internal Medicine·Scott H Stewart, Marc D Silverstein
May 18, 1996·Lancet·R Fey, N Pearson
May 21, 1999·Lancet·J Silberberg
Feb 7, 2007·Journal of the Formosan Medical Association = Taiwan Yi Zhi·Jou-Wei LinJuey-Jen Hwang
Aug 26, 1998·The American Journal of Medicine·M H CriquiR M Krauss
Feb 17, 1997·The American Journal of Medicine·A M Garber
May 5, 2004·The Urologic Clinics of North America·Mark A Moyad, Markus Sonnleithner
Apr 27, 2000·The American Journal of Medicine·D SiegelJ Meier
Jun 28, 2003·Tropical Medicine & International Health : TM & IH·S TezcanOliver Razum
Feb 5, 2004·International Journal of Health Services : Planning, Administration, Evaluation·Alexander C Tsai
Feb 12, 1999·Arteriosclerosis, Thrombosis, and Vascular Biology·H C BucherG H Guyatt
Mar 18, 1997·Circulation·A M Garber, W S Browner
Apr 1, 2000·Sozial- Und Präventivmedizin·O RazumS Tezcan
Mar 28, 2008·The Journal of Continuing Education in the Health Professions·F Daniel DuffyEric S Holmboe
May 20, 2000·Annals of Internal Medicine·A M Garber
Nov 5, 1997·Journal of the American Geriatrics Society·R BurnsR I Shorr
Sep 6, 2002·Journal of Molecular Neuroscience : MN·D Larry SparksUNKNOWN AD Cholesterol-Lowering Treatment Trial Team
Jan 30, 2014·Nanomedicine·Natalia KupferschmidtAlfonso E Garcia-Bennett
Apr 18, 2001·American Journal of Preventive Medicine·M P PignoneK N Lohr

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