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Cholestyramine-induced inhibition of salicylazosulfapyridine (sulfasalazine) metabolism by rat intestinal microflora

The Journal of Pharmacology and Experimental Therapeutics

Jul 1, 1976

Hank Pieniaszek, Theodore R Bates

PMID: 6792

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Abstract

The effect of multiple oral administration of the hypocholesterolemic agent cholestyramine (a strongly basic anion-exchange resin) on the metabolism of salicylazosulfapyridine by microflora present in the colon and cecum was assessed in conventional rats by following the time course of ...read more

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Intestines
Sulfasalazin medac
Paracolobactrum
Depression, Chemical
Metabolic Diseases
MK-135
Sulfapyridine
Feces
Ulcerative Colitis
Aminosalicylic Acids
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Cholestyramine-induced inhibition of salicylazosulfapyridine (sulfasalazine) metabolism by rat intestinal microflora

The Journal of Pharmacology and Experimental Therapeutics

Jul 1, 1976

Hank Pieniaszek, Theodore R Bates

PMID: 6792

DOI:

Abstract

The effect of multiple oral administration of the hypocholesterolemic agent cholestyramine (a strongly basic anion-exchange resin) on the metabolism of salicylazosulfapyridine by microflora present in the colon and cecum was assessed in conventional rats by following the time course of ...read more

Mentioned in this Paper

Intestines
Sulfasalazin medac
Paracolobactrum
Depression, Chemical
Metabolic Diseases

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