Cholinergic innervation of the rat's labyrinth

Experimental Brain Research
D W SchwarzH C Fibiger

Abstract

Efferent vestibular and cochlear neurons were identified in the rat's brain stem by retrograde labelling with True Blue (TB) or wheat germ agglutinin - horseradish peroxidase (WGA-HRP) injected into the utricle. Such cells were found at the same locations described in 1983 by White and Warr (ipsilateral superior olivary nucleus (LSO), bilateral latero-ventral nucleus of the trapezoid body (LTz) bilateral group E medial and lateral to the genu facialis) and, in addition, bilaterally in the caudal pontine reticular nucleus (CPR) at the level of the descending facial nerve. Cholinergic neurons were identified by counterstaining sections containing TB filled perikarya for acetylcholinesterase (AChE) following pretreatment with diisopropylfluorophosphate (DFP) or choline acetyltransferase (ChAT), by immunohistochemistry with highly specific monoclonal antibodies. Many, but not all, vestibular efferent cell bodies located in group E were shown to be cholinergic. These and other recently published data suggest that the efferent octavus system may consist of a number of chemically distinct cell groups.

Citations

Jan 1, 1997·Journal of Tongji Medical University = Tong Ji Yi Ke Da Xue Xue Bao·W KongB Hussl
Oct 16, 1987·Neuroscience Letters·B Fritzsch, U Wahnschaffe
Jan 1, 1988·Hearing Research·D W SchwarzS R Vincent
Aug 1, 1991·Current Opinion in Neurobiology·J M Goldberg
Jun 16, 2005·Neuroscience Letters·Chuan LiYing-Shing Chan
Aug 7, 1998·Brain Research. Developmental Brain Research·D Demêmes, C Broca
Aug 22, 2017·Frontiers in Physiology·Miranda A MathewsAndrew J Murray
Jun 15, 2007·The Journal of Comparative Neurology·B J KangR L Stornetta
Oct 12, 2005·The Journal of Comparative Neurology·Anne E LuebkeAnna Lysakowski
Apr 2, 2002·Neuroreport·Evan BalabanOttavio Pompeiano
Oct 1, 1991·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·P A WackymP E Micevych
Oct 1, 1994·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·A IshiyamaP A Wackym
Sep 12, 2015·The Journal of Comparative Neurology·Szilard SajgoTudor Constantin Badea
Jan 1, 1988·American Journal of Otolaryngology·D W Schwarz, I E Schwarz

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