PMID: 1202099Nov 1, 1975Paper

Cholinergic modulation of tonic immobility in the rabbit (Oryctolagus cuniculus)

Journal of Comparative and Physiological Psychology
D C HattonM E Meyer

Abstract

The present study was performed to determine the effects of the anticholinergic agent scopolamine and the cholinergic agent physostigmine on tonic immobility in rabbits. Recordings of the electroencephalographic (EEG) activity from cortex and hippocampus were also made before, during, and after each test session. Scopolamine significantly prolonged the response and produced large amplitude slow wave activity in the EEG of both cortex and hippocampus. Physostigmine significantly shortened the duration of immobility and increased rhythmic slow activity in the frequency range of 5.5-9.1 Hz in the hippocampus while producing a desynchronized cortical rhythm. It is suggested that the cortex and hippocampus play a role in modulating tonic immobility duration by inhibiting the brain-stem structures thought to control this response.

Citations

Jan 1, 1980·Physiology & Behavior·C W HennigA A Macphee
Mar 1, 1989·Physiology & Behavior·B E HurwitzM E Meyer
May 1, 1984·Pharmacology, Biochemistry, and Behavior·C W HennigB D Spencer
May 1, 1981·Behavioural Brain Research·F FarabolliniG Carli
May 1, 1981·Behavioural Brain Research·G CarliG Fontani
Sep 1, 1982·Behavioural Brain Research·G FontaniG Carli
Sep 30, 1993·Behavioural Brain Research·L Menescal-de-Oliveira, A Hoffmann
Feb 12, 2014·Journal of Comparative Physiology. A, Neuroethology, Sensory, Neural, and Behavioral Physiology·Amália Turner GiannicoFabiano Montiani-Ferreira
Jul 1, 1988·Pharmacology, Biochemistry, and Behavior·C W HennigJ L Allen
Jan 1, 1979·Mechanisms of Ageing and Development·K R Brizzee, J M Ordy
Jan 1, 1978·Behavioral Biology·D C HattonM E Meyer
Aug 9, 2011·Hormones and Behavior·Vicente Sandoval-HerreraSergio R Zamudio
Mar 1, 1988·Pain·Carlo A Porro, Giancarlo Carli

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