Nov 20, 1975

Cholinesterases from plant tissues. VI. Preliminary characterization of enzymes from Solanum melongena L. and Zea mays L

Biochimica Et Biophysica Acta
R A Fluck, M J Jaffe

Abstract

Enzymes capable of hydrolyzing esters of thiocholine have been assayed in extracts of Solanum melongena L. (eggplant) and Zea Mays L. (corn). The enzymes from both species are inhibited by the anti-cholinesterases neostigmine, physostigmine, and 284c51 and by AMO-1618, a plant growth retardant and they both have pH optima near pH 8.0. The enzyme from eggplant is maximally active at a substrate concentration of 0.15 mM acetylthiocholine and is inhibited at higher substrate concentrations. On the basis of this last property, the magnitude of inhibition by the various inhibitors, and the substrate specificity, we conclude that the enzyme from eggplant, but not that from corn, is a cholinesterase.

Mentioned in this Paper

Corn extract
Enzymes, antithrombotic
Eggplant extract
Structure-Activity Relationship
Solanum melongena antigen
Inhibitors
Pseudocholinesterase
Cholinesterase Inhibitors, Reversible
Zea mays
Cholinesterase Inhibitors

About this Paper

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