Chondroblastic osteosarcoma arising in the maxilla mimicking the radiographic and histological characteristics of cemento-osseous lesions: A case report

Molecular and Clinical Oncology
Bin-Bin LiYan Gao

Abstract

Osteosarcomas of the jaw are comparatively rare and represent only 2-10% of all osteosarcomas. We herein present a rare case of an osteosarcoma exhibiting the radiographic and histological characteristics of cemento-osseous lesions in the alveolar ridge of the maxilla. A 53-year-old male patient presented with the complaint of gradual swelling of the left maxilla over 4 years. Radiography revealed an ill-defined radioopaque mass, intimately associated with the apices of the involved teeth, without a periosteal reaction. Microscopically, a cementicle-like structure was identified in the alveolar bone. In addition, the lesion exhibited typical characteristics of chondroblastic osteosarcoma in the body of the maxilla. The tumor contained abundant osteoid and cartilage intimately associated with anaplastic tumor cells. The cartilage displayed malignant-appearing cells in lacunae, and there was crowding at the periphery of the lobule where the spindle cells formed sheets. The differential diagnosis included primary osteosarcoma, concurrent cemento-osseous dysplasia and osteosarcoma, or a secondary osteosarcoma based on a pre-existing cemento-osseous lesion. The presence of the cementicle-like structure in the alveolar bone and the i...Continue Reading

References

Aug 1, 1986·Oral Surgery, Oral Medicine, and Oral Pathology·G FortezaF López-Barea
Apr 1, 1995·International Journal of Oral and Maxillofacial Surgery·M E KouryL B Kaban
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Jun 6, 2013·Journal of Dental Research·H RoguljicI Kalajzic

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Citations

Feb 20, 2021·Australian Endodontic Journal : the Journal of the Australian Society of Endodontology Inc·Mariana Domingos PiresRonald Ordinola-Zapata

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