Chondroblastoma and chondromyxoid fibroma

The Journal of the American Academy of Orthopaedic Surgeons
Camila B R De MattosJohn P Dormans

Abstract

Chondroblastoma and chondromyxoid fibroma are benign but locally aggressive bone tumors. Chondroblastoma, a destructive lesion with a thin radiodense border, is usually seen in the epiphysis of long bones. Chondromyxoid fibroma presents as a bigger, lucent, loculated lesion with a sharp sclerotic margin in the metaphysis of long bones. Although uncommon, these tumors can be challenging to manage. They share similarities in pathology that could be related to their histogenic similarity. Very rarely, chondroblastoma may lead to lung metastases; however, the mechanism is not well understood.

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Related Concepts

Malignant Bone Neoplasm
Chondroblastoma
Myxofibroma
Bone Neoplasms
Neoplasms
Pathology
Secondary Malignant Neoplasm of Lung
Chondromyxoid Fibroma
Surgical margins
Skeletal Bone

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