Chondroid melanoma metastatic to lung and skin showing SOX-9 expression: a potential diagnostic pitfall

International Journal of Surgical Pathology
Kristopher M McKayVictor G Prieto

Abstract

Melanoma is a malignant neoplasm that shows multiple morphological appearances resembling other tumors and therefore may generate diagnostic pitfalls. In cases of metastatic melanoma, when the primary skin lesion has gone undiscovered or has not been brought to the attention of the clinician or pathologist, the metastatic lesion can be misdiagnosed as sarcoma, carcinoma, or lymphoma. Melanomas with differentiation toward mesenchymal elements are particularly perilous in this regard. Here, the authors report a case of metastatic melanoma that was misdiagnosed as extraskeletal myxoid chondrosarcoma. This case highlights the potential diagnostic pitfall posed by metastatic melanoma with chondroid matrix and SOX-9 expression.

References

Jan 1, 1985·Dermatologica·M H GrunwaldE J Feuerman
Sep 13, 2001·Journal of Cutaneous Pathology·C D AckleyC R Shea
Jan 26, 2010·The American Journal of Dermatopathology·Priya RaoVictor G Prieto

❮ Previous
Next ❯

Citations

Aug 9, 2016·Scientific Reports·Jekaterina KazantsevaKaia Palm
May 22, 2018·Journal of Cutaneous Pathology·Jasmine SalehDouglas R Fullen
Nov 2, 2018·Pathology Oncology Research : POR·Priya KumarSunita Gupta
Apr 23, 2019·The American Journal of Dermatopathology·Andrea SagginiLorenzo Cerroni
Jun 12, 2013·Advances in Anatomic Pathology·Elizabeth G Demicco
Oct 27, 2017·Journal of Cutaneous Pathology·Ali M AliAlexander J Lazar

❮ Previous
Next ❯

Related Concepts

Related Feeds

Carcinosarcoma

Carcinosarcoma is a malignant neoplasm that contains elements of carcinoma and sarcoma so extensively intermixed as to indicate neoplasia of epithelial and mesenchymal tissue. Discover the latest research on carcinosarcoma here.